tag72 nanobody

UNLABELLED An accurate and noninvasive tracer able to detect molecular events underlying the development of rheumatoid arthritis (RA) would be useful for RA diagnosis and drug efficacy assessment. A complement receptor of the Ig superfamily (CRIg) is expressed on synovial macrophages of RA patients, making it an interesting target for molecular imaging of RA. We aim to develop a radiotracer for...

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An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission.

Journal: :Hepatology 2013

Alexander W Tarr Pierre Lafaye Luke Meredith Laurence Damier-Piolle Richard A Urbanowicz Annalisa Meola Jean-Luc Jestin Richard J P Brown Jane A McKeating Felix A Rey Jonathan K Ball Thomas Krey

UNLABELLED Severe liver disease caused by chronic hepatitis C virus is the major indication for liver transplantation. Despite recent advances in antiviral therapy, drug toxicity and unwanted side effects render effective treatment in liver-transplanted patients a challenging task. Virus-specific therapeutic antibodies are generally safe and well-tolerated, but their potential in preventing and...

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Generation of a Nanobody Targeting the Paraflagellar Rod Protein of Trypanosomes

2014

Emmanuel Obishakin Benoit Stijlemans Julien Santi-Rocca Isabel Vandenberghe Bart Devreese Serge Muldermans Philippe Bastin Stefan Magez

Trypanosomes are protozoan parasites that cause diseases in humans and livestock for which no vaccines are available. Disease eradication requires sensitive diagnostic tools and efficient treatment strategies. Immunodiagnostics based on antigen detection are preferable to antibody detection because the latter cannot differentiate between active infection and cure. Classical monoclonal antibodie...

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نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

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