BACKGROUND The aim of this study was to assess the economic value of a reduced number of pills in patients infected with the immunodeficiency virus (HIV) and on highly active antiretroviral therapy by a cost-effectiveness model. METHODS An incremental cost-effectiveness analysis of efavirenz, tenofovir, and emtricitabine (TDF-FTC-EFV) as a single-tablet regimen versus a multipill regimen, wit...

BACKGROUND Raltegravir is an HIV-1 integrase inhibitor approved for use in adults, children and infants ≥4 weeks of age. As alternatives to the original film-coated tablet, a chewable ethylcellulose (EC) tablet and oral granules for suspension (GFS) have been developed for use in children. The purpose of this study was to evaluate these formulations in adults prior to use in paediatric studies....

Altace Tablets (ramipril) are supplied as tablets for oral administration containing 1.25 mg, 2.5 mg, 5 mg and 10 mg of ramipril. The inactive ingredients present are calcium sulphate dihydrate, pregelatinized starch, sodium bicarbonate, and sodium stearyl fumarate. The 2.5 mg tablet contains yellow iron oxide and FD&C yellow #6, the 5 mg tablet contains FD&C yellow #6 and FD&C red #40, and the...

ALTACE Tablets (ramipril) are supplied as tablets for oral administration containing 1.25 mg, 2.5 mg, 5 mg and 10 mg of ramipril. The inactive ingredients present are calcium sulphate dihydrate, pregelatinized starch, sodium bicarbonate, and sodium stearyl fumarate. The 2.5 mg tablet contains yellow iron oxide and FD&C yellow #6, the 5 mg tablet contains FD&C yellow #6 and FD&C red #40, and the...

Nifedipine Extended-release Tablet depends for its action on the existence of an osmotic gradient between the contents of the tablet core and fluid in the gastrointestinal tract. Drug delivery is essentially constant as long as the osmotic gradient remains constant, and then gradually falls to zero. Upon swallowing, the biologically inert components of the tablet remain intact during gastrointe...

A cost-effective design of an ultrasonic interface to a graphics tablet is accomplished by means of PIC microcontrollers. This paper analyses the design and implementation from requirements capture through high-level design to circuitry. Ultrasonic transducers enable direct placement of the tablet mechanism above an LCD so that the image is viewed as it is created. Results show that the prototy...

A 16-year-old schoolgirl presented to the emergency ward after ingestion of 1 fresh tablet of aluminum phosphide (celphos) mixed with water. According to the attendant, she vomited 8-10 times and had profuse sweating after ingestion of celphos tablet. There was no history of fever, headache, chest pain, breathlessness, convulsion, drug intake or loss of consciousness after ingestion of celphos ...

The present study investigated the use of a tablet computer to assess figure-tracing skills and their relationships with psychological (visual-perceptual processes, cognitive processes, handwriting skills) and physiological (body mass index, isometric strength of arms) parameters with school-children of second (7-8-year-olds) and fourth (9-10-year-olds) grades. We were also interested in gender...

OBJECTIVE To assess the relative efficacy and safety of zolmitriptan in the treatment of acute migraine attacks. BACKGROUND Zolmitriptan is a second-generation triptan developed for the treatment of migraine. Numerous randomized controlled trials (RCTs) have been carried out to compare different dosages and formulations of zolmitriptan against other treatments for acute migraine. METHODS Ra...

Artemisinin combination therapies are considered the mainstay of malaria treatment, but pediatric-friendly formulations for the treatment of infants are scarce. We sought to evaluate the efficacy and safety of a new dispersible-tablet formulation of dihydroartemisinin/piperaquine phosphate (DHA/PQP) in comparison to the marketed tablet (Eurartesim) in the treatment of infants with uncomplicated...