BACKGROUND The high degree of phenotypic similarity among Trichophyton species makes their identification difficult. OBJECTIVES The current study aims to establish the use of rolling circle amplification (RCA) based on internal transcribed spacer ribosomal DNA (ITS rDNA) as a powerful, simple, and rapid procedure for distinguishing closely related organisms, and specifically to identify Trich...

Pseudomonas aeruginosa and Acinetobacter baumannii are common nosocomial pathogens, well recognized for their multidrug resistance. Acyl-homoserine lactone (Acyl-HSL) based Quorum sensing (QS) is known to regulate virulence and biofilm maturation in these organisms; hence, inhibition of QS will help to control their pathogenicity. In the study, 5 plants, Rubia cordifolia, Tinospora cordifolia, ...

Quorum sensing regulates bacterial virulence determinants, therefore making it an interesting target to attenuate pathogens. In this work, we screened edible, endemic plants in Malaysia for anti-quorum sensing properties. Extracts from Melicope lunu-ankenda (Gaertn.) T. G. Hartley, a Malay garden salad, inhibited response of Chromobacterium violaceum CV026 to N-hexanoylhomoserine lactone, thus ...

A large number of Gram-negative, motile, mesophilic, violacein-producing bacteria were isolated from the soils and roots of Vaccinium macrocarpon Ait. and Kalmia angustifolia L. plants and from irrigation ponds associated with wild and cultivated cranberry bogs in Massachusetts, USA. Phylogenetic analyses of 16S rRNA gene sequences placed these isolates in a clade with Chromobacterium species, ...

Violacein is a violet pigment extracted from the gram-negative bacterium Chromobacterium violaceum. It presents bactericidal, tumoricidal, trypanocidal, and antileishmanial activities. We show that micromolar concentrations efficiently killed chloroquine-sensitive and -resistant Plasmodium falciparum strains in vitro; inhibited parasitemia in vivo, even after parasite establishment; and protect...

BACKGROUND AND OBJECTIVES Onychomycosis is a common fungal infection which has been conducted in many parts of the world. The aim of this study was to evaluate the epidemiology and to identify the aetiological factors of onychomycosis in Mazandaran province, Iran. MATERIALS AND METHODS During the period of 10 years (2003-2012) 1100 patients suspected with onychomycosis, referred to the Mycolo...