نتایج جستجو برای: syt

تعداد نتایج: 361  

Journal: :International journal of clinical and experimental medicine 2015
Hao Yang Xiaoxue Zha Yaojun Cai Fen Wang Zhangbi Wu Bo Wu Xuemei Jia Defa Zhu

The study aims to observe the impacts of thyroxine (T4) combined with donepezil (DON) on hippocampal ultrastructures and expressions of synaptotagmin-1 and SNAP-25 in adult rats with hypothyroidism. All rats were randomly divided into five groups: the normal control group (CON), the hypothyroidism group (Hypo), the T4 treatment group (T4), the DON treatment group (DON) and the T4+DON combined t...

2014
Madhurima Dhara Antonio Yarzagaray Yvonne Schwarz Soumyajit Dutta Chad Grabner Paanteha K. Moghadam Anneka Bost Claudia Schirra Jens Rettig Kerstin Reim Nils Brose Ralf Mohrmann Dieter Bruns

Abbreviations used in this paper: ANOVA, analysis of variance; ChrgA, chromogranin A; CM, membrane capacitance; Cpx, complexin; dko, double ko; EB, exocytotic burst; ko, knockout; MDis, median distance; NMJ, neuromuscular junction; NP, nitrophenyl; rms, root–mean–square; RRP, readily releasable pool; SR, sustained rate; SRP, slowly releasable pool; SybII, synaptobrevinII; Syt, synaptotagmin; wt...

Journal: :Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 2015
J Zajak P Hladík R Lischke

Synovial sarcoma is malignant mesenchymal fuso-cellular tumor with variable epithelial differentiation. We present the rare case of young female patient with primary synovial sarcoma of the liver. Molecular diagnosis was done by detection of SYT/SSX fusion transcript. Patients with sarcoma should be treated only in high specialized centres.Key words: synovial sarcoma of the liver.

Journal: :The Biochemical journal 2002
Mitsunori Fukuda

The synaptotagmin-like protein (Slp) family consists of an N-terminal Rab27-binding domain and C-terminal tandem C2 motifs, and although it has been suggested to regulate Rab27-dependent membrane trafficking, such as Ca2+-regulated granule exocytosis in T-lymphocytes [Kuroda, Fukuda, Ariga and Mikoshiba (2002) J. Biol. Chem. 277, 9212-9218], little is known about the Ca2+-binding property of th...

2015
FEN WANG XIANZHONG ZENG YANGBO ZHU DAN NING JUNXIA LIU CHUNLEI LIU XUEMEI JIA DEFA ZHU

A growing number of studies have revealed that neurocognitive impairment, induced by adult-onset hypothyroidism, may not be fully restored by traditional hormone substitution therapies, including thyroxine (T4). The present study has investigated the effect of T4 and donepezil (DON; an acetylcholinesterase (AChE) inhibitor) treatment on the hypothyroidism-induced alterations of acetylcholine (A...

2013
Julia Lee Keith Juan Bilbao Sidney Croul Lee Cyn Ang Marie-Christine Guiot John Rossiter Zeina Ghorab Cynthia Hawkins Jason Karamchandani

AIMS Pathologists are under increasing pressure to accurately subclassify sarcomas, yet neuropathologists have limited collective experience with rare sarcoma types such as synovial sarcoma. We reviewed 9 synovial sarcomas affecting peripheral nerve diagnosed by neuropathologists and explored the morphologic and immunohistochemical differences between these and MPNST. Our goal was to make pract...

Journal: :Human molecular genetics 1995
B de Leeuw M Balemans D Olde Weghuis A Geurts van Kessel

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