The present study employed an imaging mass spectrometry (IMS) method to evaluate the effect of dietary n – 3 fatty acids on the fatty acid composition in rat brain. Rats were divided into two groups and fed either an n – 3 fatty acid-deficient or adequate diet. We determined the decreased n – 3 fatty acids in the hippocampus of rats fed an n – 3 fatty acid-deficient diet compared to the control...

The aim of the present study was to examine potential protective effects of methyl N-methylanthranilate (M) and isopropyl N-methylanthranilate (I) in a rat model of acute intoxication with carbon tetrachloride (CCl4) by tracking the changes in liver morphology and function. Serum transaminase and bilirubin were significantly elevated in animals treated with CCl4 alone. A pretreatment with M and...

This study was aimed to investigate the effects of Cuminum cyminum seed aqueous extract on function and histological structure rat kidney treated with dibutyl phthalate (DBP). Eighteen albino rats weighing 190-240g aged 10-12 weeks were used for this which went 28 days. The divided into three groups (each six animals): 1st group: control given food tap water, 2nd group DBP (420mg/Kg. B.W.) wate...

To determine if phenotype and the carbohydrate type resulted in alterations brain composition obese of congenic LA/Ntul//-cp rat, groups (n= 8 rats/group) male littermate lean rats were fed standardized isocaloric diets containing 54% (w/w) cornstarch (ST diet) or sucrose (SUC from 1 until 10.5 ± 0.5 months age. The his strain develops early onset chronic hyperinsulinemia without NIDDM associat...

Maternal obesity exerts negative effects on cognitive function and behavior of the offspring. In the present study, we assessed the effects of paternal physical exercise on spatial learning ability in relation with hippocampal neuroplasticity in the rat pups born from the obese maternal rats. There were four experimental groups: paternal nonexercised male pups from normal maternal rats, paterna...

The effect of dietary undegraded carrageenan (Viscarin 402) on colon carcinogenesis was studied in female inbred F344 rats. Weanling rats were fed semipurified diets containing 0 or 15% undegraded carrageenan. At 7 weeks of age, all animals except controls were given azoxymethane (AOM) s.c. at a dose rate of 8 mg/kg body weight per week for 10 weeks or methylnitrosourea (MNU) intrarectally at a...

McKean, C. M. (1971). Archives of Disease in Childhood, 46, 608. Effects of totally synthetic, low phenylalanine diet on adolescent phenylketonuric patients. The long-term responses of 5 adolescent phenylketonuric patients to chemically-defined, synthetic diets with normal and low phenylalanine content were determined. The synthetic preparations were found capable of sustaining good health and ...