Nanoenzymes In article 2300191 by Wenli Diao, Hui Wei, Hongqian Guo, and co-workers, a Zr-CeO nanozyme is developed to possess enhanced activities mimicking superoxide dismutase catalase. Via scavenging intracellular reactive oxygen species, exerts remarkable effects on diminishing myeloid-derived suppressor cells M2-TAM immunosuppression simultaneously, eventually boosts anti-tumor immune resp...

In this study, we investigate the expression of Brucella abortus proteins in resporise to oxidative stress. The focus is on several proteins thought to be involved in bacterial protection. We show that catalase and Cu-Zn superoxide dismutase are regulated in response to H2O2 or by superoxide, whereas expression of Hsp70 and Hsp60 are not dramatically affected by oxidative stress. The regulation...

BACKGROUND Breast cancer is the most common form of cancer and the focus on finding chemotherapeutic agents have recently shifted to natural products. Piper betle is a medicinal plant with various biological activities. However, not much data is available on the anti-cancer effects of P. betle on breast cancer. Due to the current interest in the potential effects of antioxidants from natural pr...

The current study examined the toxicity of Roundup, which is a herbicide containing glyphosate that commonly used in agriculture, on Oreochromis niloticus, type freshwater fish. researchers investigated effectiveness using antioxidant enzymes as biochemical biomarkers to assess potentially toxic impact Roundup sub-lethal concentration tilapia 1.05 mg/l for 96 hours exposure. fish were exposed (...

Background: Sub-Saharan Africa is not insusceptible to the obesity epidemic, regardless of continued problem undernutrition. Increases in rates overweight and are being identified Africa, especially among women people dwelling urban populations. This study, therefore, aimed at evaluating effects ketogenic diet on markers oxidative stress (reduced glutathione (GSH), catalase (CAT), superoxide di...

Mammalian erythrocytes have large amounts of catalase, an enzyme which catabolizes hydrogen peroxide (H202). Because catalase has a low affinity for H202, others have suggested that glutathione peroxidase clears most H202 within the erythrocyte and that catalase is of little import. We hypothesized that erythrocyte catalase might function to protect heterologous somatic cells against challenge ...

The catalase level of Bacteroides distasonis (ATCC 8503, type strain) varied with the amount of hemin supplied to the medium when the cells were grown in either a prereduced medium containing 0.5% peptone, 0.5% yeast extract, and 1% glucose or in a prereduced, defined heme-deficient medium. The effect of hemin on catalase production could not be duplicated by ferrous sulfate or ferrous ammonium...

The present study tested the effects of EUK-134, a synthetic superoxide dismutase/catalase mimetic, on several indices of oxidative stress and neuropathology produced in the rat limbic system as a result of seizure activity elicited by systemic kainic acid (KA) administration. Pretreatment of rats with EUK-134 did not modify the latency for or duration of KA-induced seizure activity. It did pro...

Evaluation was performed of chemical compound contents and enzyme activities in the whole homogenate, its supernatant and sediment. Six rabbit livers were pulverized in liquid nitrogen and homogenized. After centrifugation, the contents of protein, haemoglobin, vitamin A, vitamin E, vitamin C, as well as the activities of cathepsin B, cathepsin D, superoxide dismutase, catalase, glutathione per...

The biochemical effects of ethylacetate extract of wheat (Avemar) on some serum and liver enzymes were evaluated in T. brucei infected rats. The results show significant increase in specific activities of serum aspartate transaminase (AST) in infected untreated rats when compared with infected treated rats. However, there were no significant difference in serum and liver alanine transaminase (A...