Iron±sulfur (Fe S) proteins are present in all forms of life and perform essential roles in, for example, respiration, photosynthesis, and nitrogen fixation. They contain prosthetic groups of complexed iron and TMacid-labile∫ sulfide. These Fe S clusters were identified about 40 years ago; however, it was not until the late 1990s that biosynthetic routes for in vivo assembly started to emerge. ...

agents has received considerable experimental at tention during the last few years, and a variety of mechanisms of action have been postulated to ac count for the effect. Much of this investigation has centered on the interaction of these agents with deoxyribonucleic acid (DNA) (1, 3, 4, 9, 11, 13, 19—9292)following the initial suggestion by Elmore et at. (8) that sulfur mustard probably atta...

Sulfur mustard (HD) is an alkylating agent that reacts rapidly with macromolecular targets resulting in the formation of stable adducts providing depots for markers of exposure. The purpose of this study was to validate an analytical procedure for detection of HD-plasma protein adducts and to establish the utility of the method in an HD rat inhalation study. Calibration curves were prepared in ...

BACKGROUND Mustard gas, a known chemical weapon, was used during the Iran-Iraq war of 1980-1988. We aimed to determine if exposure to mustard gas among men was significantly associated with abnormalities and disorders among progenies. METHODS Using a case-control design, we identified all progenies of Sardasht men (exposed group, n = 498), who were born at least nine months after the exposure...

The main aim in this study was to collect the experiences of Iranian researchers about sulfur mustard (SM) and provide a guideline for the prevention of abuse for this dangerous agent. We searched valid national and international databases using related key words in the two languages. We found 193 articles which had been published in medical journals. Among them, 25 articles had some implicatio...

UNLABELLED Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. METHODS One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastroduodenoscopy. Of them, 52 cases had b...

A thermophilic photosynthetic purple bacterium was isolated from the waters of a hot spring in Yellowstone National Park, Wyoming. The organism differs from all known purple bacteria in that it grows optimally at a temperature of about 50 degrees C. The isolate contains bacteriochlorophyll a and grows autotrophically, oxidizing sulfide to elemental sulfur which is then stored as globules inside...

A new species of Archaea grows at pH approximately 0.5 and approximately 40 degrees C in slime streamers and attached to pyrite surfaces at a sulfide ore body, Iron Mountain, California. This iron-oxidizing Archaeon is capable of growth at pH 0. This species represents a dominant prokaryote in the environment studied (slimes and sediments) and constituted up to 85% of the microbial community wh...

A method for the selective synthesis of sulfide clusterfullerenes Dy2S@C2n is developed. Addition of methane to the reactive atmosphere reduces the formation of empty fullerenes in the arc-discharge synthesis, whereas the use of Dy2S3 as a source of metal and sulfur affords sulfide clusterfullerenes as the main fullerene products along with smaller amounts of carbide clusterfullerenes. Two isom...

British anti-Lewisite (BAL) (2,3-dimercapto-1-propanol) is a potential therapeutic compound when used against the effects of cutaneous sulfur mustard, and a method for its determination in plasma has been developed. BAL and the internal standard (IS) ethane dithiol were isolated from plasma samples through solid-phase extraction and then reacted with 1-pentafluoropropionylimidazole, forming sta...