BACKGROUND The purpose of this study was to visualize atherosclerotic plaques independently of luminal narrowing using T1-weighted contrast-enhanced MRI. METHODS AND RESULTS Eight Watanabe heritable hyperlipidemic (WHHL) rabbits, aged 9 to 18 months, and 8 age-matched controls (New Zealand White rabbits) underwent MRI of the aortic arch before and up to 48 hours after injection of 100 micromo...

BACKGROUND Despite historical evidence of blinding trachoma, there have been no widespread contemporary surveys of trachoma prevalence in the northern states of Sudan. We aimed to conduct district-level surveys in this vast region in order to map the extent of the problem and estimate the need for trachoma control interventions to eliminate blinding trachoma. METHODS AND FINDINGS Separate, po...

In the present study we show that recombinant bacterial CotA-laccase from Bacillus subtilis is able to decolourise, at alkaline pH and in the absence of redox mediators, a variety of structurally different synthetic dyes. The enzymatic biotransformation of the azo dye Sudan Orange G (SOG) was addressed in more detail following a multidisciplinary approach. Biotransformation proceeds in a broad ...

The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses. We investigated the susceptibility of Egyptian rousettes to each of the five known ebolaviruses (Sudan, Ebola, Bundibugyo, Taï Forest, and Reston), and compared findings ...

Characterised as a bridge between the Arab-Muslim world and Black Africa; and as a melting pot where diverse ethnic, religious and language groups were related together, Sudan continues to baffle observers and analysts by protracted conflicts and crises inflicted on its population. Amid all these, major parties to the conflict accuse each other of sowing the seeds of disintegration and disunity...

AIMS To determine the general characteristics of people with mental disorders in traditional healers centres in Sudan in terms of sociodemographic profile, common clinical presentations and diagnostic features, and to look at the treatment methods and intervention procedures used in these centres for treating people with mental illness. METHODS This is a descriptive cross-sectional study usin...

background tuberculosis (tb) continues to be a major public health problem worldwide. in developing countries, the burden of the disease is explosive, as 95% of global tb patients reside and 98% of global tb deaths occur in these regions. patients’ satisfaction may play a major role in adherence to medications and hence improve tuberculosis cure rate. objectives the current study aimed firstly ...

OBJECTIVE To explore the feasibility of health systems strengthening from the perspective of international healthcare implementers and donors in South Sudan. DESIGN A qualitative interview study, with thematic analysis using the WHO health system building blocks framework. SETTING South Sudan. PARTICIPANTS 17 health system practitioners, working for international agencies in South Sudan, ...

Plasmodium falciparum is a predominant malaria species that infects humans in the African continent. A recent WHO report estimated 95% and 5% of P. falciparum and P. vivax malaria cases, respectively, in Sudan. However many laboratory reports from different areas in Sudan indicated otherwise. In order to verify, we selected four hundred suspected malaria cases from Aljabalain area located in th...

Impact of insecticide resistance in Anopheles arabiensis on effectiveness of malaria vector control in Sudan – Hmooda Kafy, National Malaria Control Programme, Sudan The objective of the trial was to assess the impact of insecticide resistance on the effectiveness of malaria vector control in Sudan and to determine the effects of different combinations of vector control intervention combination...