BACKGROUND Bangladesh is one of the few countries that may actually achieve the fifth Millennium Development Goal (MDG) in time, despite skilled birth attendance remaining low. The purpose of this paper is to examine the potential role misoprostol can play in the decline of maternal deaths attributed to postpartum hemorrhage (PPH) in Bangladesh. METHODS Using data from a misoprostol and blood...

OBJECTIVE To examine the effect of the interval between mifepristone and misoprostol administration on induction time (first misoprostol dose to abortion), total procedure time (mifepristone administration to abortion), and safety and efficacy in second-trimester induction abortion (13-24 weeks). DATA SOURCES We searched MEDLINE (1966-2012), ClinicalTrials.gov, POPLINE, and the Cochrane Contr...

OBJECTIVES To compare three methods of labour induction. DESIGN Randomised controlled trial. SETTING Academic hospitals in Johannesburg, South Africa. SUBJECTS Women with intact membranes due for induction of labour. METHOD Randomised, sealed opaque envelopes were used to allocate women to labour induction with extra-amniotic Foley catheter/titrated oral misoprostol solution (N = 174), ...

Misoprostol has revolutionized labour induction since the early 1990’s, because it is inexpensive and very effective. Eclampsia is common unless the pregnancy can be terminated by induction or by caesarean section. This study was done to determine the impact of Misoprostol used for induction of labour, on the outcome in patients with pre-eclampsia (PE) at the University of the West Indies Kings...

BACKGROUND Making misoprostol widely available for management of postpartum haemorrhage (PPH) and post abortion care (PAC) is essential for reducing maternal mortality. Private pharmacies (thereafter called "pharmacies") are integral in supplying medications to the general public in Senegal. In the case of misoprostol, pharmacies are also the main supplier to public providers and therefore have...

conclusions misoprostol plus letrozole was more effective for inducing abortion in the first trimester of pregnancy compared to misoprostol alone. results the complete abortion rate was 69.7% in the misoprostol and letrozole group and 30.3% in the misoprostol group. incomplete abortion was 32.4% in the misoprostol and letrozole group, and 67.6% in the misoprostol group (p = 0.004). bleeding, ce...

OBJECTIVE To determine the effect of misoprostol, a synthetic prostaglandin E1 analogue, on the gastrointestinal tract (GIT) symptoms associated with non-steroidal anti-inflammatory drug (NSAID) administration and on the haemoglobin value, in children. METHODS Retrospective chart review of children attending the paediatric rheumatology clinic at a tertiary referral hospital over a three year ...

Labor induction abortion is effective throughout the second trimester. Patterns of use and gestational age limits vary by locality. Earlier gestations (typically 12 to 20 weeks) have shorter abortion times than later gestational ages, but differences in complication rates within the second trimester according to gestational age have not been demonstrated. The combination of mifepristone and mis...