Background: Exposure to ionizing radiation is inevitable. Using of low-level laser therapy (LLLT) stimulates tissue repair and reduces inflammation. The objective of the present study aimed at evaluating the therapeutic efficacy of Helium-Neon (He-Ne) laser in stimulating the reparative processes in the liver of mice after whole body gamma-irradiation (WBγ-I). Materials and Methods: Two hundred...

Alternative sweeteners are widely advocated and used. However, there is insufficient scientific information to determine whether alternative sweeteners aer of value in the management of diabetes, either in improving dietary adherence or in contributing to the achievement or maintenance of a lower body weight. Each of the available sweeteners has advantages and disadvantages; no one is preferred...

DNA within cells is subject to damage from various sources. Organisms have evolved a number of mechanisms to repair DNA damage. The activity of repair enzymes carries its own risk, however, because the repair of two nearby lesions may lead to the breakup of DNA and result in cell death. We propose a mathematical theory of the damage and repair process in the important scenario where lesions are...

The kinetics of repair of radiation-induced DNA damage and recovery from radiation-induced potentially lethal damage (PLD) for fed plateau-phase 9L/Ro rat brain tumor cells were compared after single doses of 7-radiation and after combined treatment with 3 /tg of 1,3-bis(2-chloroethyl)-1 -nitrosourea (BCNU)/ml given 16 hr prior to irradiation. DNA damage and repair were assayed using alkaline f...

A total of 71 Aeromonas strains were isolated in the south of Jiangsu Province China in order to analyze the difference ofAeromonas spp. distribution between diseased fish and water environment. The sequence of 16S rDNA and gyrB demonstrated that the 71 Aeromonas isolates could be divided into 4 species, including A. veronii (55), A. hydrophila (11), A. salmonicida (3) and A. media (2). A. vero...

Chromatin dynamics modulate DNA repair factor accessibility throughout the DNA damage response. The spatiotemporal scale upon which these dynamics occur render them invisible to live cell imaging. Here we present a believed novel assay to monitor the in vivo structural rearrangements of chromatin during DNA repair. By pair correlation analysis of EGFP molecular flow into chromatin before and af...

* Department of Economics, Northwestern University, Evanston, IL 60208 (e-mail [email protected]). This research was supported in part by the Kaufmann Foundation. † Go to http://dx.doi.org/10.1257/aer.p20161126 to visit the article page for additional materials and author disclosure statement. The four contributions to this symposium develop viewpoints that are highly complementary to the ma...

BACKGROUND DNA repair is a cellular defence mechanism responding to DNA damage caused in large part by oxidative stress. There is a controversy with regard to the effect of red blood cells on DNA damage and cellular response. AIM To investigate the effect of red blood cells on H2O2-induced DNA damage and repair in human peripheral blood mononuclear cells. METHODS DNA breaks were induced in ...

The kinetics of repair of radiation-induced DNA damage and recovery from radiation-induced potentially lethal damage (PLD) for fed plateau-phase 9L/Ro rat brain tumor cells were compared after single doses of gamma-radiation and after combined treatment with 3 micrograms of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)/ml given 16 hr prior to irradiation. DNA damage and repair were assayed using ...

Many of the DNA damage-inducible genes encoding DNA repair and recombination proteins are expressed as part of the SOS response (39, 40). LexA protein represses the genes of the SOS regulon (Table 1); when DNA damage occurs, RecA protein inactivates the LexA repressor, leading to induction of the SOS response. The SOS response controls the expression of genes involved in recombination repair (d...