UNLABELLED Many fractures occur in women with moderate fracture risk caused by osteopenia. Strontium ranelate was studied in 1431 postmenopausal women with osteopenia. Vertebral fracture risk reduction of 41-59% was shown depending on the site and fracture status at baseline. This is the first report of antivertebral fracture efficacy in women with vertebral osteopenia. INTRODUCTION Women wit...

The concentrations of strontium and barium have been measured in water, sediment and the shells of mussels (Mytilus edulis) from a river system in the Sunart region of Scotland, UK. The aim was to establish the fate and mobility of these elements, which are slowly being released from old mine workings on the Strontian granites. Enhanced strontium (1500-2000 microg l(-1) and 250-290 microg l(-1)...

Using trend analysis, the author sought a possible association between perinatal mortality rates in West Germany, 1955-1993, and the fallout from atmospheric nuclear weapons testing in the years 1952-1993. The regression model used a continuously falling trend and a superimposed extra term that reflects the average strontium content in pregnant women. Mortality rates show an upward deviation th...

Strontium isotopes are a powerful tool which provide information about provenance directly from the tissues of humans rather than the grave context and burial goods. Geographical variation in strontium isotopes is primarily controlled by the underlying geology but there are many other factors that need to be considered before migratory individuals can be identified. Consequently, despite many s...

Kinetic data analysis was used to derive a six-compartment computer model which describes the in vivo [3H]25-hydroxyvitamin D3 ([3H]25-OHD3) metabolism in control and strontium rachitic chicks. Plasma concentrations of 25-OHD3 (13 pmol/ml) and 25, 25-dihydroxyvitamin D3 (0.9 pmol/ml) were 18 and 125% greater than controls, respectively, whereas the corresponding level for 1alpha,25-dihydroxyvit...

which occurs in nature in the several steps of the food chain from plants to man. This section is followed by a comprehensive bibliography of American and European references on the subject, including some Russian authors. A presentation of the authors' own experimental methods in determining the distribution of radiostrontium in bone then follows. The techniques which have been utilized includ...

Calcium absorption tests have rarely been validated for being representative for absolute bioavailability (true absorption) or for intraindividual variation. Therefore, we investigated the reproducibility of the absolute bioavailability of strontium chloride, a marker for intestinal calcium absorption, in healthy male volunteers (n = 8) by measuring the area under the plasma strontium concentra...

We present a new laser setup designed for high-precision spectroscopy on laser cooled atomic strontium. The system, which is entirely based on semiconductor laser sources, delivers 200 mW at 461 nm for cooling and trapping atomic strontium from a thermal source, 4 mW at 497 nm for optical pumping from the metastable P23 state, 12 mW at 689 nm on linewidth less than 1 kHz for second-stage coolin...

Calcium (Ca2+), strontium (Sr2+), and barium (Ba2+) are expected to exert similar chemical and pharmacological effects. The effects of barium, strontium and calcium were studied on the contractions of rat phrenic nerve-diaphragm preparations, following electrical stimulation and their interactions with nifedipine (nif) and diltiazem (DZM) were also studied. Low doses of strontium chloride (SrCl...

Substitution of calcium for strontium in LnSr2-xCaxCu2GaO7 (Ln = La, Pr, Nd, Gd, Ho, Er, Tm, and Yb) materials at ambient pressure and 975 degrees C results in complete substitution of calcium for strontium in the lanthanum and praseodymium systems and partial substitution in the other lanthanide systems. The calcium saturation level depends on the size of the Ln cation, and in all cases, a dec...