OBJECTIVES To develop an in vivo perineal hernia model, to develop a technique for using small intestinal submucosa (SIS) in perineal hernia repair, to further elucidate the biological behavior of SIS, and to compare SIS herniorrhaphy with the internal obturator muscle transposition (IOT) technique. STUDY DESIGN Prospective evaluation comparing SIS herniorrhaphy with IOT. ANIMALS Twelve adu...

Social isolation stress (SIS) in adolescence is accompanied by neurobehavioral disturbances and pathophysiological changes in certain regions of the CNS such as the hippocampus. In this study, we tested whether SIS impacts seizure susceptibility in postnatal male mice due to a role of hippocampal nitric oxide (NO). To do this, we used the pentylenetetrazole (PTZ) model of clonic seizures, open-...

Signal in space (SIS) errors are a major error source for the Global Positioning System (GPS). They are defined as any errors related to satellite transmission, mainly satellite position and clock errors. A better understanding and characterization of the signal in space errors are essential for GPS integrity, because the SIS errors are a metric to determine satellite outages or failures. The s...

this is the first report about adverse inhibitory effect of v-guard and e-guard gasoline additives against soil beneficial streptomyces. v-guard and e-guard gasoline additives are anti valve seat recession agents used in unleaded gas for old car engines in iran. they contaminate soil and groundwater by fuel leaks and spills. streptomyces are of the major contributors to the biological buffering...

Extreme ecosystems can be a source of untapped micro-organisms able to produce novel bioactive compounds of industrial interest. Consequently, in this work, 32 Actinomycetes were isolated from 6 soil samples collected from Algerian Sahara in searching for untapped producers of novel antimicrobial compounds. All the isolates were further subjected to antimicrobial screening against pathogenic ba...

Natural products produced by microorganisms are important starting compounds for drug discovery. Secondary metabolites, including antibiotics, have been isolated from different Streptomyces species. The production of these metabolites depends on the culture conditions. Therefore, the development of a new culture method can facilitate the discovery of new natural products. Here, we show that myc...

Totally 189 Streptomyces isolates were obtained from eight different soils of Cuddalore, Tamil Nadu, India. Among them, only 78 isolates were morphologically distinct. The highest diversity in the Streptomyces populations was observed in agricultural soil with minimum occurrence of antagonistic organisms. The least number of Streptomyces strains was found in coastal soil with maximum antagonist...

Genes encoding extracellular beta-lactamases of Streptomyces badius, Streptomyces cacaoi, Streptomyces fradiae and Streptomyces lavendulae were cloned and mapped in Streptomyces lividans. DNA sequence analysis of the beta-lactamase genes revealed a high overall G + C content, ranging from 71 to 75 mol%, with a G + C content of 95 mol% at the third position of the codons for all four genes. The ...