OBJECTIVES Ciprofloxacin is the most frequently used member of the fluoroquinolones during initial eradication therapy of Pseudomonas aeruginosa, as well as during acute pulmonary exacerbations. However, its long-term effect on the susceptibility of the commensal flora within the cystic fibrosis (CF) airways has not yet been examined. The aim of this study was therefore to examine the consequen...

AIM To analyze the efficacy of three different concentrations of Ocimum sanctum extract against various microorganisms, Streptococcus mutans, Streptococcus mitis, Streptococcus sanguis, Lactobacillus acidophilus. MATERIALS AND METHODS Ethanolic extract of Ocimum sanctum was prepared by the hot extraction method. The extract was diluted with an inert solvent, dimethyl sulfoxide to obtain 3 dif...

Previous studies have confirmed the association of the acid producers Streptococcus mutans and Lactobacillus spp. with childhood caries, but they also suggested these microorganisms are not sufficient to explain all cases of caries. In addition, health-associated bacterial community profiles are not well understood, including the importance of base production and acid catabolism in pH homeostas...

BACKGROUND A completely new approach to diagnose microbial agents at least one day earlier based on mass spectrometric analysis becomes possible in the microbiology laboratory: MALDI TOF: matrix-assisted laser desorption/ionisation time-of-flight. Comparison between results of the new procedure with those obtained by conventional testing is mandatory. METHODS 204 clinical isolates grown on ag...

Cystic fibrosis (CF) patient airways harbour diverse microbial consortia that, in addition to the recognized principal pathogen Pseudomonas aeruginosa, include other bacteria commonly regarded as commensals. The latter include the oral (viridans) streptococci, which recent evidence indicates play an active role during infection of this environmentally diverse niche. As the interactions between ...

Several studies have been reported on the relation of sulfonamide resistance to folic acid synthesis. Miller (Proc. Soc. Exptl. Biol. Med., 57, 151, 1944) reported that a decreased amount of folic acid was produced in cultures containing sulfanilamide by both sensitive and resistant strains of Escherichia coli, and Harrison and Clapper (Bacteriol. Proc., 1950, 39) reported loss of the ability t...

Periodontitis (PD) is a chronic infectious disease mediated by bacteria in the oral cavity. (Poly)phenols (PPs), ubiquitous in plant foods, possess antimicrobial activities and may be useful in the prevention and management of periodontitis. The objective of this study was to test the antibacterial effects of selected PPs on periodontal pathogens, on both planktonic and biofilm modes of growth....

gingivitis is an inflammatory destructive disease mainly caused by microbial plaques. gram-positive and gram-negative bacilli or cocci have been isolated from dental plaque and gingivitis. this study was going to isolate and characterize the pathogenic bacteria from gingival of 100 patients with oral gingivitis. enriched and specific media used for isolation of bacteria. identification of isola...