Matrix tablets are drug delivery devices designed to release a drug in a controlled manner over an extended period of time. We develop a cellular automaton (CA) model for the dissolution and release of a water-soluble drug and excipient from a matrix tablet of water-insoluble polymer. Cells of the CA are occupied by drug, excipient, water or polymer and the CA updating rules simulate the dissol...

Numerical simulations of Einstein’s field equations provide unique insights into the physics of compact objects moving at relativistic speeds, and which are driven by strong gravitational interactions. Numerical relativity has played a key role to firmly establish gravitational wave astrophysics as a new field of research, and it is now paving the way to establish whether gravitational wave rad...

We perform an analytic investigation of the stability of line-driven disk winds, independent of hydrodynamic simulations. Our motive is to determine whether or not line-driven disk winds can account for the wide/broad UV resonance absorption lines seen in cataclysmic variables (CVs) and quasi-stellar objects (QSOs). In both CVs and QSOs observations generally indicate that the absorption arisin...

PURPOSE Three-dimensional (3D) magnetic resonance phase contrast imaging (PC-MRI) allows non-invasive diagnosis of pulmonary hypertension (PH) and estimation of elevated mean pulmonary arterial pressure (mPAP) based on vortical motion of blood in the main pulmonary artery. The purpose of the present study was to compare the presence and duration of PH-associated vortices derived from different ...

Developments in information technology are providing methods to improve current design practices, where uncertainties about various design elements can be simulated and studied from the design inception. Energy and thermal simulations, improved design representations and enhanced collaboration using digital media are increasingly being used. This paper discusses research on the use of Building ...

Cloud computing has recently emerged as a new paradigm for hosting and delivering services over the Internet. Task consolidation problem in cloud computing systems became an important approach to streamline resource usage which improves energy efficiency. The task consolidation is also known as workload consolidation problem which is the process of assigning set of tasks to set of resources wit...

BACKGROUND Diffusion tensor imaging provides information about the location of white matter tracts within the human brain. For neurosurgery, this imaging technique is of major interest in order to minimize the risk of postoperative neurological deficits. In preoperative planning, fiber tracking algorithms based on streamline propagation are used in order to reconstruct major fiber tracts. The r...

BACKGROUND Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of this study was to present a novel technique using a two-tensor unscented Kalma...

  Micro scale gas flows has attracted significant research interest in the last two decades. In this research, the fluid flow of gases in the stepped micro-channel at a wide range of Knudsen number has been analyzed with using the Lattice Boltzmann (MRT) method. In the model, a modified second-order slip boundary condition and a Bosanquet-type effective viscosity are used to consider the veloci...

In recent years the work on vector field visualization has been concentrated on LIC-based methods. In this paper we propose an alternative solution for the visualization of unsteady flow fields. Our approach is based on the computation of temporal series of correlated images. While other methods are based on pathlines and try to correlate successive images at the pixel level, our approach consi...