The mammalian oocyte has played a prominent role in the development of the science of Cryobiology. Following up on the success of spermatozoa cryopreservation in the late 1940's, attempts to cryopreserve rabbit oocytes using glycerol as the cryoprotectant were undertaken. Unfortunately, the outcomes of these early studies were rather disappointing. The recalcitrance of mammalian oocytes to cryo...

In the precast structures, optimization of structural elements is of great interest mainly due to a more rationalized way that elements are produced. There are several elements of precast prestressed concrete that are objects of study in optimization processes, as the prestressed joist applied in buildings slabs. This article inquires into cost minimization of continuous and simply supported sl...

Mixed-model assembly lines are increasingly accepted in many industrial environments to meet the growing trend of greater product variability, diversification of customer demands, and shorter life cycles. In this research, a new mathematical model is presented considering balancing a mixed-model U-line and human-related issues, simultaneously. The objective function consists of two separate com...

background: this study aimed to examine the impact of ego-resilience and family function on quality of life in childhood leukemia survivors. methods: this study targeted 100 pediatric leukemia survivors, who visited the pediatric hemato-oncology center in south korea from aug to dec 2011. a structured questionnaire of ego-resilience, family function and quality of life used to collect data thro...

Search-based optimization methods have been used for software engineering activities such as software testing. In the field of software testing, search-based test data generation refers to application of meta-heuristic optimization methods to generate test data that cover the code space of a program. Automatic test data generation that can cover all the paths of software is known as a major cha...

nowadays, the environmental impact of transportation project and, especially air pollution impacts, are major concerns in evaluating transportation projects. based on this concern, beside definition of traditional objective functions like total travel time and total investment cost, different type of environmental related function is considered as objective function in urban network design. in ...

In this research study, energy, exergy and economic analyses is performed for a combined cycle power plant (CCPP) with a supplementary firing system. The purpose of this analyses is to evaluate the economic feasibility of a CCPP by applying an optimization techniques based on Evolutionary algorithms. Actually, the evolutionary algorithms of Firefly, PSO and NSGA-II are applied to minimize the c...

In this paper we consider logspline density estimation for data that may be lefttruncated or right-censored. For randomly left-truncated and right-censored data the product-limit estimator is known to be a consistent estimator of the survivor function, having a faster rate of convergence than many density estimators. The product-limit estimator and B-splines are used to construct the logspline ...

MOTIVATION We propose a stepwise approach to identify recombination breakpoints in a sequence alignment. The approach can be applied to any recombination detection method that uses a permutation test and provides estimates of breakpoints. RESULTS We illustrate the approach by analyses of a simulated dataset and alignments of real data from HIV-1 and human chromosome 7. The presented simulatio...