Objective: Both of selective serotonin reuptake inhibitors (SSRIs) and estrogen can modulate emotion and cognition function in post-menopause women, moreover SSRIs can influence estrogen system in rats and aquatic wildlife but most of them for reproductive ability. The aim of this study was to investigate the possible relationship between SSRI, estrogen, and emotion and cognition in post-menopa...

We demonstrate a significantly high incidence of human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy (HAM)-or tropical spastic paraparesis (TSP)-like symptoms in WKA rats after injection with HTLV-1-producing MT-2 cells, while no symptoms were observed in F344 rats injected with MT-2 cells or in control WKA rats. Five of the eight (63%) WKA rats injected with MT-2 cells showed HAM...

Although perturbation techniques are widely applied to analyze nonlinear problems in science and engineering, they are however so strongly dependent on small parameters appeared in equations under consideration that they are restricted only to weakly nonlinear problems. For strongly nonlinear problems which don’t contain any small parameters, perturbation techniques are invalid. So, it seems ne...

A state of T-cell activation, reflected by a marked degree of spontaneous proliferation in vitro, exists among patients with human T-cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) but not in those with retroviral-induced adult T-cell leukemia (ATL). We wished to define the mechanism by which the immune activation of circulating cells from HA...

the underlying mechanisms leading to the development of human t-cell lymphotropic virus type i (htlv-i) associated myelopathy/tropical spastic paraparesis (ham/tsp) in htlv-i infected individuals are not fully understood. host genetic factors appear to be involved as risk factors for developing ham/tsp. we investigated the possible contribution of interleukin-10 (il-10) as a risk factor to ham/...

INTRODUCTION This study aimed to investigate the relationship between levels of depression and anxiety symptoms and quality of life, self-esteem in obesity. METHODS Fifty-two subjects whose Body Mass Index (BMI) is 30 kg/m2 and over and 43 control whose BMI is normal were recruited for this study. The socio demographic data form, Hamilton Depression Rating Scale (HAM-D17), Hamilton Anxiety Ra...

BACKGROUND Human T-lymphotropic virus type 1 (HTLV-1) -associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. Since the disease course of HAM/TSP varies among patients, there is a dire need for biomarkers capable of predicting the rate of disease progression. However, there have been no studies to date that have compared the prognostic values o...

The rising prevalence of obesity and the vulnerability of the pediatric age group have highlighted the critical need for a careful consideration of effective, safe, remedial and preventive dietary interventions.  Amylose starch (RS2) from high-amylose maize (HAM) ferments in the gut and affects body weight.   One hundred and ten children, of 7-8 (n=91) or 13-14 (n=19) years of age scored the se...

BACKGROUND Patients with mixed anxiety-depressive disorder (MADD) suffer both anxiety and depression. Antidepressants, especially, selective serotonin reuptake inhibitors are among agents of choice for treating this condition. OBJECTIVES This study compared the efficacy of Cipram® with its generic, citalopram. PATIENTS AND METHODS Forty adult outpatients (between 18 to 55 years of age) with...

Human T-lymphotropic virus type I (HTLV-1) is an endemic virus in Iran and other regions that is associated with multiple diseases including adult T-cell leukemia/ lymphoma and a chronic debilitating neuroinflammatory disease, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is seen in approximately 2% of HTLV-1-infected people with symptoms such as back pain, weakne...