We investigate the possibility to detect giant planets that are still embedded in young circumstellar disks. Based on models with different stellar, planetary, and disk masses, and different radial positions of the planet we analyze the resulting submillimeter appearance of these systems. We find that the influence of the planet on the spectral energy distribution could not be distinguished fro...

A coupled-inductor-based high step-up step-down DC-DC converter with bidirectional capability suitable for electric vehicle (EV) applications is proposed in this paper. The voltage gain both and operations increased by a two-winding coupled inductor. current ripple the low-voltage port low making it renewable energy sources. In addition, number of components causes efficiency to be competitive ...

In this paper, a new step-up/step-down AC-AC converter is designed by switched capacitor (SC) techniques. The main features of the proposed SC AC-AC converter are the symmetrical converter topology and the absence of magnetic elements. Owing to the symmetrical converter topology, the number of capacitors in the proposed AC-AC converter is fewer than that in the conventional SC AC-AC converter. ...

A low dose step-up and step-down regimen for induction of ovulation using urinary FSH was compared in a prospective randomized fashion in 37 normogonadotropic clomiphene-resistant oligo- or amenorrheic infertile women. The objectives was to assess potential differences in duration of treatment, ovarian stimulation (serum FSH levels), and response [serum estradiol (E2) levels and number and size...

Asthma is a common chronic airways disease. The goal of asthma management is to control symptoms while minimizing the side effects of treatment. Following a period of stable asthma, clinicians should consider stepping down treatment. This approach is recommended by current guidelines. Step-down has been studied for several types of asthma drug regimens, and certain approaches may have lower ris...

Ontogeny of step-down passive avoidance (PA) was studied in 174 Wistar rats at the age of 2, 3, 4, 6, 8 and 13 weeks. Latency to the first descent from the safe bench (DL), number of descents (DN), time to criterion meeting (TC) and time during which animals were shocked (TS), were evaluated within learning (L) and two consecutive retention tests (R1 and R2); R1 took place at short to intermedi...

In recent years, a change in the treatment goals for patients with Crohn's disease (CD) has come under intense discussion. Whereas 10 years ago treatment was initiated mainly in reaction to acute flares of the disease aimed to improve clinical symptoms, the focus now has changed to the prevention of damage to the intestinal wall. The prevention of structural damage by achievement of 'mucosal he...

This paper investigates an open issue related to false discovery rate (FDR) control of step-up-down (SUD) multiple testing procedures. It has been established in earlier literature that for this type of procedure, under some broad conditions, and in an asymptotical sense, the FDR is maximum when the signal strength under the alternative is maximum. In other words, so-called “Dirac uniform confi...

Dean Russell Richey of the Candler School of Theology announced recently that he will step down as dean following the 2005–06 academic year to return to his teaching and scholarship. Richey has served as Candler dean since July 2000, when he left his position as professor of church history at the Duke Divinity School. From 1986–97 he served as associate dean for academic programs at Duke, and f...

Richter and McCann (2007) presented a median-based multiple comparison procedure for assessing evidence of group location differences. The sampling distribution was based on the permutation distribution of the maximum median difference among all pairs, and provides strong control of the FWE. This idea is extended to develop a step-down procedure for comparing group locations. The new step-down ...