Aziridine-based cofactor mimics have been synthesized and are shown to undergo methyltransferase-dependent DNA alkylation. Notably, each cofactor mimic possesses an azide functionality, to which can be attached an assortment of unnatural groups following methyltransferase-dependent DNA delivery. DNA duplexes modified with these cofactor mimics are capable of undergoing the Staudinger ligation w...

Post-biotinylation of the alkyl azide derivative of trifluoromethyl phenyldiazirine (TPD) was elucidated to apply a photoaffinity biotinylation technique. A photo-modified polyvinilidene difluoride (PVDF) membrane was used as a photolabeled component and we introduced biotin by Staudinger-Bertozzi ligation. The 15 pmol amount of biotinylated reagent was still effective for the visualization of ...

This study was conducted on the Geometridae fauna of Hasankeyf district Batman between 2018 and 2020. 27 different localities were visited 2.870 specimens in total collected using insect net UV light traps mostly nighttimes, since majority species are nocturnal. The taxonomic investigations revealed presence 66 within 39 genera 5 subfamilies (Desmobathrinae, Geometrinae, Ennominae, Larentiinae,...

Abstract Being 100 years since the birth of macromolecular science, 2020 was meant to be “Year Polymers,” but instead it turned into year pandemic. Actually two are not unrelated —most PPE is made polymer, and without health-care response COVID-19 would have looked completely different been far more treacherous. But that’s another story, one with which IUPAC Polymer Division engaging [1]. Here ...