OBJECTIVE The aetiology and clinical features of status epilepticus (SE) are described, with the aim of defining any relationship between risk factors and clinical outcome. METHODOLOGY A retrospective review was performed of 37 Chinese children admitted to Queen Mary Hospital, Hong Kong, from 1989 to 1993 with the diagnosis of SE. RESULTS Eighty-six per cent had onset before 5 years of age;...

Generalised convulsive status epilepticus continues to be a medical emergency with high morbidity and mortality. The patient with convulsive status epilepticus has continuous or rapidly repeating seizures. In contrast, symptoms in nonconvulsive status epilepticus are often more subtle which frequently delays the diagnosis. This case describes a 27 year-old man who presented after a first seizur...

Abbreviations: VGKC: Voltage-gated Potassium Channel; NMDAR: N-methyl, D-aspartate Receptor; LGI 1: Leucin-Rich Glioma-Inactivated-1; CASPR 2: Contact in-Associated Protein-2; SE: Status Epilepticus; WBC: White Blood Count; ALT: Alanine Transaminases; AST: Aspartate Transaminases; HSV-1: Herpes Simplex Virus; PCR : Polymerase Chain Reaction; EEG: Electro Encephalogram; CT: Computed Tomography; ...

There are two main types of animal models of TLE, kindling and status epilepticus (SE). In the kindling model (3), spaced and repeated stimulations of the brain evoke afterdischarges (ADs) that increase progressively in duration and in the severity of clinical/ behavioral symptoms. Kindling allows good control of the timing of ADs, but a relatively large number of kindled ADs ( 200) is required...

Limb shaking (LS) is often confused with focal motor seizures. Distinguishing between both is crucial, because LS may represent an indicator of severe carotid occlusive disease and patients are at high risk of stroke. We report the case of a patient with occlusive carotid stenosis without definite stroke who develops partial motor status epilepticus (SE). Clinical, neuroimaging and electroencep...

Sialidosis, a rare lysosomal storage disorder is caused by a deficiency of the enzyme α-N-acetyl neuraminidase, resulting from mutations in the NEU1 gene. Its main phenotypes are Sialidosis types I (milder form) and II (earlier onset). Sialidosis type II is characterized by developmental delay, macular cherry-red spot, visceromegaly, coarse facies, dysostosis multiplex, and myoclonus. We report...

Background Status epilepticus (SE) is a neurological emergency, with short-term mortality ranging from 0.9 to 3.6% in children. The disease burden of SE includes morbidity, treatment costs, and mortality. Various scoring tools for predicting outcomes adult cases have been widely studied, but there are few children SE.
 Objective To evaluate the usefulness status pediatric patients severity...

Children frequently experience status epilepticus (SE), a neurologic emergency. Based on current findings in the medical literature, this systematic review aimed to published literature of updates epidemiology Status pediatric patients Saudi Arabia. Because they are reliable sources, PubMed and EBSCO Information Services will be used as search databases for publications study. seizures, mental ...

ABKÜRZUNGEN Abb. Abbildung ADD 1 after-discharge duration 1 (Nachentladungsdauer 1) ADD 2 after-discharge duration 1 (Nachentladungsdauer 2) A. dest. Aqua destillata ADT after-discharge threshold (Nachentladungsschwelle) BLA basolaterale Amygdala BrdU Bromodesoxyuridin bsp. Beispiel bzgl. bezüglich bzw. beziehungsweise c control (Kontrolle) ca. zirka cm Zentimeter d day (Tag) DCX Doublecortin d...

Prolonged, refractory status epilepticus is a rare clinical syndrome that is associated with severe morbidity and mortality. Lacosamide is a newly approved medication for treatment of partial onset seizures in adults, which has a novel mechanism of action. Experimental data and recent reports suggest that lacosamide could be effective in status epilepticus. We report a child with prolonged, ref...