نتایج جستجو برای: stat
تعداد نتایج: 11747 فیلتر نتایج به سال:
OBJECTIVE Exposure of beta-cells to inflammatory cytokines leads to apoptotic cell death through the activation of gene networks under the control of specific transcription factors, such as interferon-gamma-induced signal transducer and activator of transcription (STAT)-1. We previously demonstrated that beta-cells lacking STAT-1 are resistant to cytokine-induced cell death in vitro. The aim of...
To determine the role of interleukin (IL)-6 in the increased ozone (O3)-induced inflammation and injury observed in obese vs. lean mice, lean wild-type and leptin-deficient obese (ob/ob) mice were injected with anti-IL-6 antibody (Ab) or isotype control Ab 24 h before exposure to either O3 (2 ppm for 3 h) or room air. Four or 24 h after O3 exposure, bronchoalveolar lavage (BAL) was performed, a...
Recently various kinds of cardiac stem/progenitor cells have been identified and suggested to be involved in cardiac repair and regeneration in injured myocardium. In this review, we focus on the roles of JAK-STAT signaling in cardiac stem/progenitor cells in cardiomyogenesis. JAK-STAT signaling plays important roles in the differentiation of stem cells into cardiac lineage cells. The activatio...
We have studied inclusive muon events using all the data collected by the TOPAZ detector at √ s = 58GeV with an integrated luminosity of 273pb. From 1328 inclusive muon events, we measured the ratio Rqq̄ of the cross section for qq̄ production to the total hadronic cross section and forward-backward asymmetry AqF B for b and c quarks. The obtained results are Rbb̄ = 0.13 ± 0.02(stat) ± 0.01(syst),...
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