We studied the effect of chronic oral exposure to lead acetate (PbA) on the sensitivity of RBC to hemolysis and whether the sensitivity could be decreased by feeding the rats with extract of medicinal mushroom Ganoderma lucidum. Three groups of rats, control, PbA-exposed, and G. lucidum (Gl)+PbA, were used. PbA (3 mM) was administered via drinking water and G. lucidum extract by gavage at 300 m...

INTRODUCTION Extracorporeal circulation (EC) is very important in cardiac surgery but causes significant damage to the blood, including hemolysis. OBJECTIVE To quantify the rate of hemolysis at different times during EC in elective coronary artery bypass grafting. METHODS We measured rates of hemolysis of 22 patients at 6 different times during myocardial revascularization during EC: T0 - b...

INTRODUCTION Our goal was to determine if the hemolysis among blood samples obtained in an emergency department and then sent to the laboratory in a pneumatic tube system was different from those in samples that were hand-carried. METHODS The hemolysis index is measured on all samples submitted for potassium analysis. We queried our hospital laboratory database system (SunQuest(®)) for potass...

BACKGROUND Three kinds of conditions should be considered to reduce free hemoglobin production using an autologous cell salvage device. They are the negative suction pressure, the size of suction tip, and the air contact during suction. We want to examine which condition is the most important factor to produce free hemoglobin. METHODS One pack of red blood cell and one pack of fresh frozen pl...

A colony of a yellow pigment forming, nonhemolytic Micrococcus species (tentatively identified as Micrococcus luteus) was found on a human blood agar plate close to a hemolytic staphylococcal colony. It was also noted that the zone of hemolysis of this Staphylococcus (the term Micrococcus is not used here for this organism to avoid confusion with the other) was slightly but definitely indented ...

The technique of differential agglutination of red cells, introduced by Ashby ( 1 ), has been widely used to measure the life span of red cells following transfusion. The technique of differential hemolysis was investigated as a possible alternative to this method in an attempt to separate more easily the surviving donor cells from those of the recipient. Differential hemolysis was first used b...

Eleven patients undergoing open heart surgery were studied by means of a technic previously developed by us to quantitate intravascular and extravascular hemolysis. Endogenous production of carbon monoxide, which correlates quantitatively with red blood cell and hemoglobin catabolism, was measured preoperatively, 5 hr postoperatively, and 24 hr postoperatively. Rates of plasma hemoglobin catabo...

During intravascular hemolysis in human disease, vasomotor tone and organ perfusion may be impaired by the increased reactivity of cell-free plasma hemoglobin (Hb) with NO. We experimentally produced acute intravascular hemolysis in a canine model in order to test the hypothesis that low levels of decompartmentalized or cell-free plasma Hb will severely reduce NO bioavailability and produce vas...

Transfusion-acquired babesiosis can be an asymptomatic or self-limited febrile hemolytic illness in a healthy host. A persistent, relapsing, and/or fulminant course with the development of life-threatening complications may be seen in immunocompromised or splenectomized patients. As in malaria, erythrocyte parasitemia is often associated with nonimmune hemolysis, and can be treated with erythro...

1. The titer of an individual insulin antiserum measured by hemagglutination agrees favorably with the titer of the same antiserum as measured by immune hemolysis. 2. In contrast, a marked decrease is noted in the immune hemolysis titers relative to hemagglutination titers of antisera prepared against three different sialic acid-containing proteins (human chorionic gonadotropin, rabbit transfer...