OBJECTIVE Manipulation of cotton operating room towels within the abdominal cavity in open abdominal surgery has been associated with the formation of peritoneal adhesions. In a rabbit model, the use of standard cotton operating room towels is compared to the Lap Pak, a silicone bowel-packing device, to determine the potential for reducing the risk of adhesions. METHODS Thirty rabbits were ra...

Background & aims: Adhesion and fibrotic bands formation is one of the most important post-surgical complication in pelvic and abdominal surgeries. Major studies in prevention of adhesion formation have based on antioxidant and anti-inflammatory agents. Silymarin, Silybum marianum extract contains compounds with antioxidant, anti-inflammatory and fibrinolytic activities thus could reduce adhesi...

In this study we assessed the effectiveness of fluid viscosities placed in the peritoneal cavity to prevent postoperative peritoneal adhesions. Thirty-six Wistar albino female rats (average weight: 160 +/- 30 g, average age: 6.5 months) were divided into three groups of equal number. A standard adhesion pattern was formed in each group. Then, 3 ml isotonic sodium chloride solution (relative vis...

HYPOTHESIS Phospholipids and icodextrin reduce peritoneal adhesions resulting from general peritonitis without promoting abscess formation. DESIGN Evaluation of adhesion reduction fluids in a randomized animal study using a standardized peritonitis model. SETTING Experimental animal model in a university laboratory. INTERVENTIONS In 60 rats, experimental peritonitis was induced using the ...

the objective of this study was to determine the effectiveness of topical administration of honey in prevention of or reduction in post-surgical peritoneal adhesions in dog. the study was conducted on 18 adultfemale mixed-breed dogs with a mean ± sd weight of 20 ± 4.25 kg. a standardized surgical trauma (serosaltrauma model) was made in the dogs’ descending colon to induce adhesion formation. t...

Reversal after Hartmann’s procedures is technically challenging and followed by high morbidity rate. One the main risk factors of complications need to dissect peritoneal adhesions for optimal access large bowel, which leads bowel deserosing, intestine lumen opening late perforation. Meanwhile, question remains unresolved: there a total adhesiolysis during operations end colostomy takedown, or ...