The prevalence and molecular types of extended-spectrum beta-lactamases (ESBLs) were determined during a 1-year period in unselected clinical nonduplicate isolates of Escherichia coli (n = 1,738), Klebsiella pneumoniae (n = 436), and Klebsiella oxytoca (n = 208), cultured at the University Medical Centre Nijmegen, The Netherlands. Isolates identified as ESBL producer by the Phoenix automated sy...

this article aims to provide a simple robust method to test the parameters of a normal population by using the new diagnostic tool called the “forward search” (fs) method. the most commonly used procedures to test the mean and variance of a normal distribution are student’s t test and chi-square test, respectively. these tests suffer from the presence of outliers. we introduce the fs version of...

BACKGROUND Proteus species cause a variety of community- and hospital-acquired illnesses. Synthesis of β-lactamases is the predominant mechanism for resistance to β-lactam antibiotics. Among the β-lactamases, extended spectrum β-lactamases (ESBLs) and AmpC β-lactamases are the most common. AIM The objective of this study was to determine the occurrence of ESBL and AmpC β-lactamases in Proteus...

OBJECTIVES Extended-spectrum beta-lactamase (ESBL) producing bacteria have an important role in nosocomial infections. Due to the limited availability of information about the molecular epidemiology of ESBL producing bacteria in Mashhad, we decided to investigate about TEM, CTX and SHV ESBLs among urinary Escherichia coli isolates in Mashhad, a city in northeast Iran. MATERIALS AND METHODS On...

BACKGROUND Extended spectrum β-lactamase (ESBL) producing Escherichia coli has tremendously increased worldwide and it is one of the most common causes of morbidity and mortality associated with hospital-acquired infections. This could be attributed to association of multi drug resistance in ESBL producing isolates. The present study was aimed to determine the antimicrobial sensitivity profile ...

objective(s) different types of extended spectrum beta-lactamases (esbls) are encountered in the clinical settings worldwide. there are a few studies regarding the prevalence of esbl genes among klebsiella pneumoniae isolates at tehran especially those of blaper and blactx. the aim of this study was to determine the prevalence of blashv, blatem ,blaper and blactx genes among clinical k. pneumon...

BACKGROUND Pseudomonas aeruginosa is the most common pathogen causing nosocomial infections. Resistance of P. aeruginosa strains to broad-spectrum cephalosporins may be mediated by extended-spectrum β-lactamases (ESBLs). OBJECTIVES We intended to investigate the prevalence of ESBLs and antimicrobial susceptibilities of P. aeruginosa isolated from patients in Zahedan, Iran. MATERIALS AND MET...

Objectives: The aim of this prospective study was to assess the extent of dissemination of extended-spectrum  -lactamase (ESBL)-producing Enterobacteriaceae at the hospital level in the United Arab Emirates (UAE). Materials and Methods: A total of 662 Escherichia coli and Klebsiella pneumoniae samples were collected from three UAE hospitals between January and December 2008. ESBL screening and...

BACKGROUND Escherichia coli is an important bacterial species based on incidence and associated infection severity. Some E. coli strains produce extended-spectrum beta lactamase (ESBL) and are called ESBL-producing E. coli. These strains are resistant to most classes of cephalosporin and a number of other classes of antibiotics. Plasmids carrying qnr genes have been found to transmit quinolone ...