A novel high-throughput label-free resonant waveguide grating (RWG) imager biosensor, the Epic® BenchTop (BT), was utilized to determine the dependence of cell spreading kinetics on the average surface density (v(RGD)) of integrin ligand RGD-motifs. v(RGD) was tuned over four orders of magnitude by co-adsorbing the biologically inactive PLL-g-PEG and the RGD-functionalized PLL-g-PEG-RGD synthet...

We studied unique cerebral blood flow (CBF) responses to cortical spreading depression in mice using a novel two-dimensional CBF imaging technique, laser speckle flowmetry. Cortical spreading depression caused a triphasic CBF response in both rat and mouse cortex. In rats, mild initial hypoperfusion (approximately 75% of baseline) was followed by a transient hyperemia reaching approximately 220...

Protein-coated resorbable synthetic polymeric nanofibrous membranes are promising for the fabrication of advanced skin substitutes. We fabricated electrospun polylactic acid and poly(lactide-co-glycolic acid) nanofibrous membranes and coated them with fibrin or collagen I. Fibronectin was attached to a fibrin or collagen nanocoating, in order further to enhance the cell adhesion and spreading. ...

This paper explores some perverse features that can emerge when social contracts are moved from a social vacuum to a setting of social interdependence. In particular we note incentives that might exist in conjunction with externality problems that yield situations in which: (1) social contracts reduce social wealth; (2) sub-global social contracts are Pareto inferior to the absence of social co...

Acknowledgements: We thank members of the Onnela lab for feedback on earlier versions of this paper. Abstract Understanding how person-to-person contagious processes spread through a population requires accurate information on connections between population members. However, such connectivity data, when collected via interview, is often incomplete due to partial recall, respondent fatigue or st...

small precipitation with temporal and spatial variation of rainfall is the main responsible factors on flood occurrence in arid and semi arid regions. floods in their regions usually contain high concentration of sediments which when they are deposited on the surface of lands, they change the properties of soils of the area. in this research, the effect of floodwater spreading on physic-chemica...

In this paper we present an approach to check resource consumption contracts using an off-theshelf static analyzer. We propose a set of annotations to support resource usage specifications, in particular, dynamic memory consumption constraints. Since dynamic memory may be recycled by a memory manager, the consumption of this resource is not monotone. The specification language can express both ...

Privacy-preserving Messaging and Search: A Collaborative ApproachbyGiulia Cecilia FantiDoctor of Philosophy in Engineering – Electrical Engineering and Computer SciencesUniversity of California, BerkeleyProfessor Kannan Ramchandran, Chair In a free society, people have the right to consume and share public data without fear of retribu-tion. However, today’s technological...

After entering into supply contracts, ...rms often later renegotiate the terms of those contracts. For example, ...rms that obtain market demand information after signing supply contracts may bene...t by renegotiating the contracts to allow buyers facing poor market conditions to purchase less than their contractual commitment and allowing buyers facing favorable conditions to purchase more. Co...

An eecient retrieval of a relatively small number of relevant cases from a huge case base is a crucial subtask of Case-Based Reasoning (CBR). In this article, we present Case Retrieval Nets, a memory model that has recently been developed for this task. The main idea is to apply a spreading activation process to the case memory structured as a Case Retrieval Net in order to retrieve cases being...