Background: Amylin and Salmon Calcitonin belong to the calcitonin family of peptides and have high affinity binding sites in the rat spinal cord. The aim of this study was to characterize receptors for Amylin and Salmon Calcitonin functionally in the spinal cord of rats. We assessed the expression of c-Fos in response to intraplantar formalin in the lumbar regions of the spinal cord in consciou...

background and objective: deprenyl is a drug for the treatment of parkinson’s disease, where the dopaminergic neurons are the target of this drug. several reports also documented that deprenyl has an effect on the sensory and motor neurons. there are some reports about the mode of action of deprenyl on motoneurons as a neuroprotective agent, while others believe that deprenyl acts as a neurores...

background ischemic injury of the spinal cord during the surgical repair of thoracoabdominal aortic aneurysms might lead to paraplegia. although a number of different mechanisms have been proposed, the exact cause of paraplegia has remained unknown, hampering the development of effective pharmacologic or other strategies for prevention of this condition. a number of studies suggested that cyclo...

Spinal leptomeningeal metastasis occurs rarely in solid tumors, and the prognosis is extremely poor. Adenocarcinomas and small-cell carcinomas are the most common histological type detected among lung tumors. A 58-year-old man with a history of squamous-cell lung carcinoma with mediastinal invasion and brain metastasis was examined because of his low back pain and weakness in both lower limbs. ...

background: over the years, various types of orthoses have been designed to assist subjects with spinal cord injury (sci) to stand and walk. however, the functional performance of the orthoses has not been adequate, that is, patients experience stability problems, consume excessive energy during ambulation, and generally require assistance in donning and doffing the devices. this research is ai...

background and aim : acute injuries of the spine and spinal cord are causing the greatest amount of disability. they produce high cost outcomes for patients and society psychologically and economically. knowing the epidemiology of these injuries play an important role in planning for prevention and conservative treatment. but now, we have little information about this in our country. the aim of...

In most series of neoplasms of the spinal canal, spinal cord and its leptomeninges, the incidence of meningioma group comprises approximately 25%. The incidence of multiple meningiomas is small when compared with the frequency of its single occurrence. In the majority of cases, their multiplicity is intracranial and spinal. Multiple meningiomas confined exclusively to the spinal canal are extre...

Meningiomas are typically benign, slowly growing tumors. Meningiomas of the spine are most commonly intradural, extramedullary lesions and account of 25% – 46% of all spinal cord tumors in adults (Peker et al., 2005). Approximately 80% of spinal meningiomas occur in the thoracic spine, followed in frequency by cervical and lumbar lesions (Helseth et al., 1989; Levy et al., 1982; Roux et al., 19...

Intramedullary spinal schwannomas are rare benign spinal cord tumors and are easily misdiagnosed because of the imaging characteristics shared with intramedullary glioma. Correct preoperative definitive diagnosis is essential for treatment and prognosis. To improve the preoperative diagnostic strategy, clinical and imaging data of seven patients with intramedullary spinal schwannoma (6 men, mea...

background & importance: acute autonomic system impairment can be dangerous and life-threatening, and a clinician should be aware of its occurrence possibility. according to the anatomy of this system, spinal cord lesions could disturb its function. there are many reports of autonomic dysreflexia in spinal cord i njuries especially spinal cord trauma. case presentation: a 28 year-old man with a...