نتایج جستجو برای: sphingosine 1 phosphate

تعداد نتایج: 2821340  

Journal: :Journal of Investigative Dermatology 2022

Extrinsic factors, such as air pollutants and ultraviolet irradiation (UVR), accelerate premature aging, a correlation between levels of skin aging symptoms has been reported. Diesel particulate matter, major source pollution, helps initiate some diseases, including diseases. We recently demonstrated that diesel extract (DPE) activates nicotinamide adenine dinucleotide phosphate (NADPH) oxidase...

Journal: :The Journal of pharmacology and experimental therapeutics 2015
Yugesh Kharel Emily A Morris Molly D Congdon Steven B Thorpe Jose L Tomsig Webster L Santos Kevin R Lynch

Sphingosine 1-phosphate (S1P) levels are significantly higher in blood and lymph than in tissues. This S1P concentration difference is necessary for proper lymphocyte egress from secondary lymphoid tissue and to maintain endothelial barrier integrity. Studies with mice lacking either sphingosine kinase (SphK) type 1 and 2 indicate that these enzymes are the sole biosynthetic source of S1P, but ...

Journal: :Journal of Biological Chemistry 2002

Journal: :American Journal of Physiology-Renal Physiology 2019

Journal: :World Journal of Biological Chemistry 2010

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