نتایج جستجو برای: sonodynamic therapy

تعداد نتایج: 653817  

Journal: :Exploration 2021

ExplorationVolume 1, Issue 2 20210321 INSIDE FRONT COVEROpen Access Inside Front Cover: (EXP2 2/2021) First published: 30 October 2021 https://doi.org/10.1002/EXP.20210321AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version article.I have rea...

Journal: :Anticancer research 2011
Tadahiro Ohmura Takeo Fukushima Hirotomo Shibaguchi Shin Yoshizawa Tooru Inoue Masahide Kuroki Kazunari Sasaki Shin-Ichiro Umemura

BACKGROUND 5-Aminolevulinic acid (5-ALA) has already been applied clinically as a photosensitizer. In this study, sonodynamically induced selective antitumour effect of 5-ALA for deep-seated lesions was evaluated. MATERIALS AND METHODS First, normal rat brains were sonicated via a transducer placed on the dural surface to confirm safe acoustic conditions for normal rat brains. One week after ...

Journal: :Cureus 2023

Cancer patients had limited treatment options for decades, such as surgery, chemotherapy, and radiation therapy, alone or combined. However, there have been substantial improvements in recent years with the introduction of stem cell hormone anti-angiogenic treatments, immunotherapy, dendritic cell-based targeted ablation nanoparticles, natural antioxidants, radionics, chemodynamic sonodynamic f...

2014
Hanjun Zhang Xing Liu Youbin Liu Yin Wu Hongxi Li Chengbin Zhao Huazhe Li Qinggang Meng Wei Li

OBJECTIVE The aim of the present study was to explore the potential for hematoporphyrin monomethyl ether-Sonodynamic Therapy (HMME-SDT) treatment of hypertrophic scars within rabbit ears. METHODS 60 white rabbits were randomly divided into five groups: (1) untreated controls, (2) lesioned, (3) lesioned + HMME, (4) lesioned + US (Ultrasound), and (5) lesioned +HMME-SDT. After induction of a le...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016
Yuanyuan Guo Zengxiang Dong Yuanqi Shi Wei Wang Lu Wang Jing Sun Xin Sun Zhen Tian Jianting Yao Zhitao Li Jiali Cheng Ye Tian

BACKGROUND/AIMS Sonodynamic therapy (SDT) is a localized ultrasound-activated therapy for atherosclerosis when combined with a sonosensitizer, 5-aminolevulinic acid (ALA), but whether it can prevent cardiac fibrosis has not been studied. In the present study, we evaluated the effects SDT on fibrogenesis in rat cardiac fibroblasts. METHODS The primary cardiac fibroblasts were isolated from rat...

2015
Yongning Li Qi Zhou Zheng Hu Bin Yang Qingsong Li Jianhua Wang Jinhua Zheng Wenwu Cao Ferenc Gallyas

OBJECTIVE Sonodynamic therapy (SDT) is promising for treatment of cancer, but its effect on osteosarcoma is unclear. This study examined the effect of 5-Aminolevulinic Acid (5-ALA)-based SDT on the growth of implanted osteosarcoma and their potential mechanisms in vivo and in vitro. METHODS The dose and metabolism of 5-ALA and ultrasound periods were optimized in a mouse model of induced oste...

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