نتایج جستجو برای: solution phase peptide synthesis

تعداد نتایج: 1546114  

Journal: :International Journal of Peptide Research and Therapeutics 2013

Journal: :Organic & biomolecular chemistry 2006
Séverine Poupart Cédric Boudou Philippe Peixoto Marc Massonneau Pierre-Yves Renard Anthony Romieu

The synthesis and photophysical properties of a new terpyridine-based europium(III) chelate (Eu (TMT)-AP3) designed for peptide and protein labelling in aqueous solution phase is described. In order to obtain a stable, easy to handle, versatile and efficient labelling agent, a reactive aminopropargyl arm has been introduced onto the terpyridine moiety. As preliminary biochemical applications th...

Journal: :Molecules 2016
Omar F Luna Johana Gomez Constanza Cárdenas Fernando Albericio Sergio H Marshall Fanny Guzmán

The deprotection step is crucial in order to secure a good quality product in Fmoc solid phase peptide synthesis. 9-Fluorenylmethoxycarbonyl (Fmoc) removal is achieved by a two-step mechanism reaction favored by the use of cyclic secondary amines; however, the efficiency of the reaction could be affected by side reactions and by-product formation. Several aspects have to be taken into considera...

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