نتایج جستجو برای: soluble st2

تعداد نتایج: 90441  

2014
Qing Zhao Guangjie Chen

Interleukin-33 (IL-33) is a new cytokine of interleukin-1 family, whose specific receptor is ST2. IL-33 exerts its functions via its target cells and plays different roles in diseases. ST2 deletion and exclusion of IL-33/ST2 axis are accompanied by enhanced susceptibility to dominantly T cell-mediated organ-specific autoimmune diseases. It has been reported that IL-33/ST2 pathway plays a key ro...

Journal: :Psychological review 2007
Howard Bowman Brad Wyble

A detailed description of the simultaneous type, serial token (ST2) model is presented. ST2 is a model of temporal attention and working memory that encapsulates 5 principles: (a) M. M. Chun and M. C. Potter's (1995) 2-stage model, (b) a Stage 1 salience filter, (c) N. G. Kanwisher's (1987, 1991) types-tokens distinction, (d) a transient attentional enhancement, and (e) a mechanism for associat...

Journal: :Journal of the American College of Cardiology 2007
James L Januzzi W Frank Peacock Alan S Maisel Claudia U Chae Robert L Jesse Aaron L Baggish Michelle O'Donoghue Rahul Sakhuja Annabel A Chen Roland R J van Kimmenade Kent B Lewandrowski Donald M Lloyd-Jones Alan H B Wu

OBJECTIVES The aim of this study was to examine the value of measurement of the interleukin-1 receptor family member ST2 in patients with dyspnea. BACKGROUND Concentrations of ST2 have been reported to be elevated in patients with heart failure (HF). METHODS Five hundred ninety-three dyspneic patients with and without acute destabilized HF presenting to an urban emergency department were ev...

Journal: :Circulation. Heart failure 2013
G Michael Felker Mona Fiuzat Vivian Thompson Linda K Shaw Megan L Neely Kirkwood F Adams David J Whellan Mark P Donahue Tariq Ahmad Dalane W Kitzman Ileana L Piña Faiez Zannad William E Kraus Christopher M O'Connor

BACKGROUND ST2 is involved in cardioprotective signaling in the myocardium and has been identified as a potentially promising biomarker in heart failure (HF). We evaluated ST2 levels and their association with functional capacity and long-term clinical outcomes in a cohort of ambulatory patients with HF enrolled in the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Trainin...

2013
Dana C. Blok Koenraad F. van der Sluijs Sandrine Florquin Onno J. de Boer Cornelis van ’t Veer Alex F. de Vos Tom van der Poll

Interleukin-1 receptor like 1 (ST2) is a negative regulator of Toll-like receptor (TLR) signaling. TLRs are important for host defense during respiratory tract infections by both influenza and Streptococcus (S.) pneumoniae. Enhanced susceptibility to pneumococcal pneumonia is an important complication following influenza virus infection. We here sought to determine the role of ST2 in primary in...

Journal: :The New England journal of medicine 2013
Mark T Vander Lugt Thomas M Braun Samir Hanash Jerome Ritz Vincent T Ho Joseph H Antin Qing Zhang Chee-Hong Wong Hong Wang Alice Chin Aurélie Gomez Andrew C Harris John E Levine Sung W Choi Daniel Couriel Pavan Reddy James L M Ferrara Sophie Paczesny

BACKGROUND No plasma biomarkers are associated with the response of acute graft-versus-host disease (GVHD) to therapy after allogeneic hematopoietic stem-cell transplantation. METHODS We compared 12 biomarkers in plasma obtained a median of 16 days after therapy initiation from 10 patients with a complete response by day 28 after therapy initiation and in plasma obtained from 10 patients with...

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