The co-digestion of two problematic and available wastes, namely Organic Fraction Municipal Solid Waste (OFMSW) and biological sludge, was carried out in this work. Biochemical Methane Potential (BMP) tests are a useful tool for determining the best substrate and co-digestion configurations, however there are some methodologies destined to save costs and time from this process by using the theo...

We present the results from our deep (16 12 hr) Westerbork Synthesis Radio Telescope (WSRT) observations of the approximately 7 deg2 Bootes Deep Field, centered at 14h32m05 975, 34 16047>5 (J2000.0). Our survey consists of 42 discrete pointings, with enough overlap to ensure a uniform sensitivity across the entire field, with a limiting sensitivity of 28 lJy (1 rms). The catalog contains 3172 d...

An efficient method has been developed for the salicylaldehyde ester-mediated ligation of unprotected peptides at serine (Ser) or threonine (Thr) residues. The utility of this peptide ligation approach has been demonstrated through the convergent syntheses of two therapeutic peptides--ovine-corticoliberin and Forteo--and the human erythrocyte acylphosphatase protein (∼11 kDa). The requisite pep...

Mild and efficient methods for site-specific methylation of peptide backbone amides are important tools for chemists seeking to modulate the pharmacokinetic properties of peptide drugs. The Mitsunobu reaction was used to selectively methylate N-trifluoroacetamide (Tfa) protected peptides on-resin. The Tfa group was removed quickly and completely by reduction with excess NaBH4, and it was shown ...

C-Terminal cysteine peptide acids are difficult to access without epimerization of the cysteine astereocenter. Diversification of the C-terminus after solid-phase peptide synthesis poses an even greater challenge because of the proclivity of the cysteine a-stereocenter to undergo deprotonation upon activation of the C-terminal carboxylic acid. We present herein two general strategies to access ...