OBJECTIVE To determine whether patients developing ulcers had previously been identified as being at high risk of ulceration using the Scottish Care Information-Diabetes Collaboration (SCI-DC) ulcer risk score and whether the risk score predicts ulcer healing. RESEARCH DESIGN AND METHODS All patients attending the diabetes foot clinic with an ulcer had been assessed for foot ulcer risk using ...

BACKGROUND/OBJECTIVE A high prevalence of Helicobacter pylori infection has been reported in Iran. Although the importance of H. pylori in the induction of peptic ulcer disease is clearly defined, only few studies have addressed its role in bleeding from peptic ulcers. We evaluated the role of H. pylori in peptic ulcer bleeding. METHODS Patients with acute peptic ulcer bleeding (PUB) and thos...

Osyris quadripartita (OQ) Salzm. ex Decne. has been used to treat peptic ulcer disease in Ethiopian folk medicine, but its efficacy has not been validated. The present study was therefore carried out to evaluate the anti-ulcer activity of 80% methanol leaf extract of OQ in rats. The effect of OQ extract on gastric ulcer in rats in pylorus ligation-induced and ethanol-induced models was studied ...

AIM To estimate the age-specific prevalence of anti-ulcer drug use and to calculate the usage of different anti-ulcer drugs over 5 years within the universal health insurance program in Taiwan area. METHODS The National Health Insurance Research Database in Taipei supplied the cohort data sets of 200 000 people. The ambulatory and inpatient claims of the cohort from 1997 to 2001 were analyzed...

The herbal medicines derived from various plants extracts are being increasingly utilized to treat a wide variety of clinical diseases 1 . Besides their action as gastroprotectives, flavonoids also act in healing of gastric ulcers 2 . The study was designed to investigate the anti-ulcer effect of chloroform extract of Chrozophora plicata leaves (600mg/kg) against experimentally induced ulcer mo...

OBJECTIVE To determine the frequency of peptic ulcer disease in patients on nonsteroidal anti-inflammatory drugs (NSAID). METHODS Record of eight hundred and twenty consecutive patients undergoing upper gastrointestinal (GI) endoscopy; from January 1998 to December 2000 were reviewed. The endoscopic diagnosis varied from gastritis, peptic ulcer to duodenitis. The use of NSAID was documented b...

OBJECTIVE Most of the literature about Curling's ulcer was published from 1960 through 1980. Therefore, an updated study of Curling's ulcer is needed. We analyzed the risk factors affecting ulcer incidence in burn patients. METHODS We retrospectively analyzed the medical records of burn patients who were admitted to two burn centers. We collected information about the general characteristics ...

Vernal Shield ulcer is a rare sight threatening corneal manifestation of vernal keratoconjunctivitis. This study is designed to report management of a refractory shield ulcer that did not respond to variety of medications but healed in 1 week after surgical debridement of ulcer base. A 12-year old Omani boy with H/O vernal conjunctivitis since 5 years on ketotifen eye drops presented with a shi...

Introduction: Subfascial Endoscopic Perforator Surgery (SEPS) is a minimally invasive technique to treat incompetent perforating veins. Incompetent perforators are implicated in venous ulcer and in varicose veins recurrence. Complete closure of all perforating veins is the only predictor of ulcer healing. Analysis of our results is the objective of this study. Methods: Fifty (50) patients with ...

BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of the most commonly used medicines and proven to be effective for certain disorders. Some people use NSAIDs on daily basis for preventive purpose. But a variety of severe side effects can be induced by NSAIDs. Studies have shown that edible natural ingredients exhibit preventive benefit of gastric ulcer. This paper reviews th...