Although tissue-derived high mobility group box 1 (HMGB1) is involved in many aspects of inflammation and tissue injury after trauma, its role in trauma-induced immune suppression remains elusive. Using an established mouse model of peripheral tissue trauma, which includes soft tissue and fracture components, we report here that treatment with anti-HMGB1 monoclonal antibody ameliorated the trau...

The article referred to in Mr. van de Water's letter is a prospective case series bringing attention to soft-tissue restriction as a potential source of knee dysfunction. The article describes treatment of chronic pain conditions seven months or more after injury, diagnosis (which included ITBS), and ongoing care. Editors agree that description of and any reevaluation of those diagnoses, as wel...

athletic therapy today © 2009 Human Kinetics Att 14(1), pp. 2-4 SOFT TISSUE trauma initiates an inflammatory response that increases the local tissue temperature. Characteristics of inflammation include increased blood flow, edema accumulation, and passage of leukocytes into the tissue spaces. Leukocytes play a central role in removal of infectious agents and tissue debris, but they can also be...

Open hindfoot injuries result from high-energy trauma and include soft tissue disruption, joint dislocations, with possible chondral and osseous injuries. The term “total talus dislocation”, is an uncommon open hindfoot injury associated with talar extrusion. However, a total talus dislocation without extrusion has not been reported. This case presents an open hindfoot injury with dislocations ...

We report a case with gunshot to the pelvis. The injury site was the soft tissue between the rectum and urinary bladder. Several days later, the bullet was expulsed spontaneously during voiding. In the literature, only a few case reports have described spontaneous expulsion of an intravesical bullet. A 19-year-old male was wounded on the left hip by gunshot. Radiographic examinations showed a b...

BACKGROUND Management of tibial fractures associated with soft tissue injury remains controversial. Previous studies have assessed perfusion of the fractured tibia and surrounding soft tissues in the setting of a normal soft tissue envelope. The purpose of this study was to determine the effects of muscle contusion on blood flow to the tibial cortex and muscle during reamed, intramedullary nail...

Acute spinal cord injury (SCI) is one of the most common causes of severe disability and mortality after trauma. Magnetic resonance imaging (MRI) can identify different levels of SCI, but sometimes unable to detect the associated soft tissue injuries. The role of MRI with contrast in patients with SCI has not been studied. This is the first study in human to compare the efficacy of MRI with and...

background :soft tissue profile can be widely different in various populations. furthermore, this profile can be also continues to change throughout life. however, there are few studies that quantitatively evaluate the soft tissue profile in iranian population. in order to determine normal reference values of facial parts in our populations, we aimed to measure standards for facial soft tissue ...

background: abdominal circumference (ac), biparietal diameters (bpd) and femoral length (fl) are now the main parameters used to obtain estimated fetal weight (efw). although the role of soft tissue parameters in determining fetal weight was proved but clinical attention to mid-thigh soft tissue thickness (stt) is limited. objective: to find the impression of stt on birth weight (bw) and repres...