Stem bromelain that had been irreversibly inhibited with 1,3-dibromo[2-(14)C]-acetone was reduced with sodium borohydride and carboxymethylated with iodoacetic acid. After digestion with trypsin and alpha-chymotrypsin three radioactive peptides were isolated chromatographically. The amino acid sequences around the cross-linked cysteine and histidine residues were determined and showed a high de...

The verdin-type Chromophore of denatured C-phycocyanin (1) from Spirulina platensis is reduced to the corresponding rubin (2 a) by sodium borohydride. The structure assigned is in agreement with the uv-vis spectroscopic properties of the product and was deduced from model studies with free bile pigments. Analogous model studies using sodium dithionite demonstrated a two-fold reactivity for this...

The cell wall lipopolysaccharide of Escherichia coli 011 l-B4 was degraded by (a) acid hydrolysis and (b) by treatment with periodate, followed by reduction with sodium borohydride and mild acid hydrolysis. The various oligosaccharides produced by these procedures were isolated and characterized by chemical and enzymatic methods. Procedure (I released all of the colitose (3,6-dideoxy-~-xylohexo...

The disulfates of unconjugated, and glycineand taurine-conjugated bile acids have been synthesized. Cholic acid derivatives appropriately protected were sulfated with sulfur trioxidetriethylamine complex in pyridine in the usual manner. Subsequent hydrolysis and/or sodium borohydride reduction provided the desired disulfates of cholates in satisfactory yields. Dihydroxy: lated bile acid disulfa...

The cell wall lipopolysaccharide of Escherichia coli 011 l-B4 was degraded by (a) acid hydrolysis and (b) by treatment with periodate, followed by reduction with sodium borohydride and mild acid hydrolysis. The various oligosaccharides produced by these procedures were isolated and characterized by chemical and enzymatic methods. Procedure (I released all of the colitose (3,6-dideoxy-~-xylohexo...

Synlett 2003, No. 4, Print: 12 03 2003. Art Id.1437-2096,E;2003,0,04,0542,0546,ftx,en;D28903ST.pdf. © Georg Thieme Verlag Stuttgart · New York ISSN 0936-5214 Abstract: Treatment of an α-amino acid with N-bromosuccinimide in water at pH 5 or in an alcoholic-aqueous ammonium chloride mixture, followed by addition of nickel(II) chloride and sodium borohydride, effected an overall decarboxylation v...

An efficient, general procedure for highly chemoselective reductive mono-alkylation of ammonia with ketones is reported. Treatment of ketones with ammonia in ethanol and titanium(IV) isopropoxide, followed by in situ sodium borohydride reduction, and a straightforward workup afforded primary amines in good to excellent yields. Reductive alkylation of ammonia with aldehydes, on the other hand, a...

the selective reduction of oximes with sodium borohydride (nabh4) in the presence of nano cu and charcoal was investigated. cu nanoparticles are widely used as catalysts; efficacious catalyst: copper and copper alloy nanometer feature high efficacy and selectivity, and can be used as catalyst in some reactions. we have shown that nabh4 in the presence of charcoal is an efficient protocol for th...