Maintenance of neuropathic pain caused by peripheral nerve injury crucially depends on the phosphorylation of GluN2B, a subunit of the N-methyl-d-aspartate (NMDA) receptor, at Tyr1472 (Y1472) and subsequent formation of a postsynaptic density (PSD) complex of superficial spinal dorsal horn neurons. Here we took advantage of comparative proteomic analysis based on isobaric stable isotope tags (i...

BACKGROUND After peripheral nerve injury, spontaneous ectopic activity arising from the peripheral axons plays an important role in inducing central sensitization and neuropathic pain. Recent evidence indicates that activation of spinal cord microglia also contributes to the development of neuropathic pain. In particular, activation of p38 mitogen-activated protein kinase (MAPK) in spinal micro...

Masjid Merupakan tempat ibadah bagi umat Islam. Di Indonesia, bangunan masjid tersebar hampir diseluruh wilayah nusantara dengan bentuk,luasan dan skala pelayanan yang beragam. Dengan berkembangnya di berbagai kawasan Indonesia maka bekembang pula jumlah dibangun. Sementara terus mengikuti perkembangan Standar Bangunan Gedung dunia secara dinamis berubah ke arah lebih baik aman, seperti peratur...

This paper examines the history of the various actual and proposed interconnectors between New South Wales and Victoria into South Australia. It covers the period from the earliest proposal for a regulated interconnector to the recent Victoria Supreme Court review and the latest ministerial proposals. It finds, inter alia, that the Supreme Court decision is likely to have strengthened, in a ben...

<p>Emas merupakan logam mulia yang dapat dijadikan investasi karena nilainya terus naik dari waktu ke waktu. Barang – barang emas berbentuk batangan, granula, lembaran, perhiasan dan benda seni. Penjaminan mutu kadar diatur dalam SNI 13-3487-2005 13-3771-1995 muda. Pada saat ini beredar memiliki mulai 3,33% hingga 99,99% (<em>fine gold</em>). Terdapat nilai belum ke-dua terseb...