Two small cell lung cancer (SCLC) cell lines were established from pericardia! and pleura! effusions of a patient with histopathologically proven SCLC of the oat cell type. Chemotherapy was administered without response during the 148-day period prior to the establishment of the first cell line, SCLC-22H, and some of the same drugs were admin istered in the 15 days prior to the establishment of...

In social insects, colony-level complexity may emerge from simple individual-level behaviors and interactions. Emergent global properties such as colony size, which can be viewed as a consequence of life history traits, may influence individual-level behaviors themselves. The effects of colony size on productivity, body size, behavioral flexibility, and colony organization are examined here by ...

Distribution centers (DCs) play important role in maintaining the uninterrupted flow of goods and materials between the manufacturers and their customers.This paper proposes a mathematical model as the bi-objective capacitated multi-vehicle allocation of customers to distribution centers. An evolutionary algorithm named non-dominated sorting ant colony optimization (NSACO) is used as the optimi...

distribution centers (dcs) play important role in maintaining the uninterrupted flow of goods and materials between the manufacturers and their customers.this paper proposes a mathematical model as the bi-objective capacitated multi-vehicle allocation of customers to distribution centers. an evolutionary algorithm named non-dominated sorting ant colony optimization (nsaco) is used as the optimi...

Immunization of rabbits from a closed colony with streptococcal Group A-variant vaccines identified about two-thirds of them as low and heterogeneous responders. One-third of the rabbits showed a restriction of the response independent from the magnitude. Selective breeding from one monoclonal high-responder male and two restricted high-responder female rabbits succeeded in segregation of high-...