BACKGROUND Making an automatic diagnosis based on virtual slides and whole slide imaging or even determining whether a case belongs to a single class, representing a specific disease, is a big challenge. In this work we focus on WHO Classification of Tumours of the Central Nervous System. We try to design a method which allows to automatically distinguish virtual slides which contain histopatho...

Two special slides, one in front of one eye and one in front of the other eye, were placed in the housings of a synoptophore. The slides were originally designed for the diagnosis and measurement of cyclodeviation, but they were utilised in this study for the measurement of torsional fusional vergence. This was measured by rotating one of the housings of the synoptophore and noting the point of...

INTRODUCTION Standardization and validation of the color displayed by digital slides is an important aspect of digital pathology implementation. While the most common reason for color variation is the variance in the protocols and practices in the histology lab, the color displayed can also be affected by variation in capture parameters (for example, illumination and filters), image processing ...

Aim: To evaluate the effect of ligation method on friction and the efficacy of the new slick elastomeric modules (TP Orthodontics, USA) and slide elastomeric modules (Leone Orthodontics, Italy) which claim to reduce friction at the module/wire interface. Materials and methods: Slick and slide modules were compared with regular modules, modules tied in figure of eight fashion, tight stainless st...

The goal of this work is to learn from nature about the magnitudes of side-chain motions that occur when proteins bind small organic molecules, and model these motions to improve the prediction of protein-ligand complexes. Following analysis of protein side-chain motions upon ligand binding in 63 complexes, we tested the ability of the docking tool SLIDE to model these motions without being res...

The usefulness of serial study of C reactive protein in the early detection of neonatal septicaemia was evaluated in a neonatal unit using a commercially available latex agglutination slide test as a rapid screening method and electroimmunoassay as a reference method for C reactive protein determination. A positive latex test was obtained in 11 infants with verified septicaemia (positive blood ...

BACKGROUND Immune cell infiltrates (ICI) of tumors are scored by pathologists around tumor glands. To obtain a better understanding of the immune infiltrate, individual immune cell types, their activation states and location relative to tumor cells need to be determined. This process requires precise identification of the tumor area and enumeration of immune cell subtypes separately in the stro...

OBJECTIVES With the objective of bringing clinical decision support systems to reality, this article reviews histopathological whole-slide imaging informatics methods, associated challenges, and future research opportunities. TARGET AUDIENCE This review targets pathologists and informaticians who have a limited understanding of the key aspects of whole-slide image (WSI) analysis and/or a limi...

Microarray data are subject to multiple sources of measurement error. One source of potentially significant error is the settings of the instruments (laser and sensor) that are used to obtain the measurements of gene expression. Because ‘optimal’ settings may vary from slide to slide, operators typically scan each slide multiple times and then choose the reading with the fewest over-exposed and...

In this paper, we propose a new multi-modal behavioural biometric that uses features collected while the user slide-unlocks the smartphone to answer a call. In particular, we use the slide swipe, the arm movement in bringing the phone close to the ear and voice recognition to implement our behaviour biometric. We implemented the method on a real phone and we present a controlled user study amon...