According to both definitions of US Centers for Disease Control and Prevention World Health Organization, Neglected Tropical Diseases (NTDs) are a group preventable treatable parasitic, viral, bacterial diseases that affect more than one billion people globally. They generally afflict the indigent patients world historically have not received as much attention other diseases. NTDs tend thrive i...

BACKGROUND Uganda has active foci of both chronic and acute HAT with the acute zoonotic form of disease classically considered to be restricted to southeast Uganda, while the focus of the chronic form of HAT was confined to the northwest of the country. Acute HAT has however been migrating from its traditional disease focus, spreading rapidly to new districts, a spread linked to movement of inf...

Flagellar calcium binding proteins are expressed in a variety of trypanosomes and are potential drug targets for Chagas disease and African sleeping sickness. We report complete NMR chemical shift assignments of the flagellar calcium binding protein calflagin Tb24 of Trypanosoma brucei. (BMRB no. 18011).

I n the early part of the twentieth century, human African trypanosomiasis (HAT), also known as sleeping sickness, decimated the population in many parts of sub-Saharan Africa. In the 1930s, the colonial administrations, conscious of the negative impact of the disease on its territories, established disease control programmes. Systematic screening, treatment, and follow-up of millions of indivi...

A survey to determine the role of local Glossina species on the transmission of human sleeping sickness has been carried out in the Ikoma/Seronera/Kilimafedha triangle. Three different tsetse species were encountered; they were G. swyn¬ nertoni, G. pallidipes and G. brevipalpis. Out of 6,348 G. swynnertoni and 623 G. pallidipes examined not a single carried salivary gland infection. G. swynnert...

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The quantitative proteomics data here reported are part of a research article entitled "Increased acute immune response during the meningo-encephalitic stage of Trypanosoma brucei rhodesiense sleeping sickness compared to Trypanosoma brucei gambiense", published by Tiberti et al., 2015. Transl. Proteomics 6, 1-9. Sleeping sickness (human African trypanosomiasis - HAT) is a deadly neglected trop...