Adenoid cystic carcinoma (ACC) is a rare malignant tumor of the salivary glands, with higher frequency in the submandibular gland, a prolonged clinical course, and poor long-term survival. It tends to metastasize to lungs, bone, liver, brain, and rarely to skin. Comprehensive skin examination and appropriate follow-up is recommended, since cutaneous metastasis represents disease progression, re...

We present a case of a 64-year-old gentleman who developed a renal cell carcinoma (RCC) metastasis to his lower lip following successful treatment of the primary tumour. RCC is a common kidney tumour but skin metastases are considered rare. The authors describe the findings of this case and discuss the presentation, investigations and management of RCC skin lesions.

Cutaneous metastases from bladder malignancies are rare. We report the case of a 74 year old man who underwent cysto-prostatectomy and adjuvant chemotherapy for a pT3b N+ bladder transitional cell carcinoma. Four months later, he presented with skin disseminated pigmented lesions. Skin biopsy confirmed cutaneous metastasis from urothelial carcinoma.

Abstract Melanoma is the most dangerous type of cancer, with a high rate metastasis. The conventional method treating skin melanoma photodynamic therapy, yet this phototherapy has several side effects. In addition, photosensitizers used are relatively expensive and toxic. Thus, developing methods cancer using laser only promising area research. Here we present in vitro effects cell culture afte...

zosteriform metastasis is a rare clinical distribution from spreading neoplasms of every organ to the skin. tumors most often arise from a n internal o r hematologic malignancy. w e report a 69-year-old man, a known case of malignant melanoma of the left heel. in this case, multiple red-brown metastatic nodules appeared four months after diagnosis. distribution of metastatic lesions resembled a...

granular cell tumor is a rare benign neoplasm most commonly appears in the head and neck region, especially in the tongue, cheek mucosa, and palate. occurrence in limbs is even rarer. these tumors account for approximately 0.5% of all soft tissue tumors. granular cell tumor can also affect other organs including skin, breast, and lungs. local recurrence and metastasis is potentially higher in m...

Cutaneous metastasis from gastric adenocarcinoma is uncommon, and the eyelid is a rare metastatic site. Three patterns of clinical presentation of eyelid metastasis have been described: nodular, infiltrative, and ulcerated. The infiltrative pattern, also known as an inflammatory diffuse pattern or mask-like metastasis, can be easily misdiagnosed as cellulitis or contact dermatitis. Here, we rep...

Chronic inflammation plays important roles at different stages of cancer development, including carcinogenesis, tumor invasion, and metastasis, but molecular mechanisms linking inflammation to cancer development have not been fully clarified. Here, we report that expression of angiopoietin-like protein 2 (Angptl2), recently identified as a chronic inflammation mediator, is highly correlated wit...

Merkel cell carcinoma (MCC) is a rare skin tumor that usually occurs on the head, neck, or extremities of elderly patients; it has a high incidence of local recurrence, regional lymph node metastasis, and subsequent distant metastasis. We report a MCC that developed rapidly on the left corner of the upper lip of a 100-year-old woman. An incisional skin biopsy was performed to confirm MCC. Compu...