Venous gangrene is a rare condition. We report a case of venous gangrene, treated successfully with thrombolytic therapy and subsequently by skin grafting.

The tumescent technique involves the injection of large volumes of dilute local anaesthetic such as lidocaine or bupivacaine, with or without adrenaline solution, into subcutaneous fat, obtaining swelling and firmness (tumescence) of the surgical area and also creating regional anaesthesia of the skin and subcutaneous tissue that allows cutaneous surgery without pain. In particular, in cutaneou...

A 26-year old woman presented for evaluation of extensive edema, erythema, sinus tract formation and purulent drainage from the left lower extremity after trauma from a wooden object approximately three months prior. Skin biopsies and blood cultures revealed Phaeoacremonium parasiticum consistent with a diagnosis of phaeohyphomycosis. Despite hospitalization and initial treatment with several a...

BACKGROUND Although autologous fat grafting is widely accepted for breast reconstruction, its indications remain limited to minor contour deformities after reconstruction and small deformities after breast-conserving surgery. The authors describe a case series of total or nearly total breast reconstructions treated with the perioperative use of a vacuum-based external tissue expander (i.e., the...

Engineered skin substitutes (ESSs) have been reported to close full-thickness burn wounds but are subject to loss from mechanical shear due to their deficiencies in tensile strength and elasticity. Hypothetically, if the mechanical properties of ESS matched those of native skin, losses due to shear or fracture could be reduced. To consider modifications of the composition of ESS to improve homo...

AIM to present a therapeutic algorithm for chronic venous insufficiency complicated with ulceration, using etiologic treatment combined with local treatment by negative pressure wound therapy (NPWT) before and after skin grafting. MATERIAL AND METHOD we are discussing a 59 years-old patient with a lower leg gigantic, circumferential trophic lesion. The aetiology was combined, post-traumatic a...

Engineering of skin substitutes provides a prospective source of advanced therapies for treatment of acute and chronic skin wounds. Hypothetically, engineering of skin substitutes can allow deliberate fabrication of biologic materials with properties that address specific patho-biologic conditions (e.g., burns, scars, cutaneous ulcers, congenital anomalies). By design and incorporation of speci...

Epidermal stem cells have been in clinical application as a source of culture-generated grafts. Although applications for such cells are increasing due to aging populations and the greater incidence of diabetes, current keratinocyte grafting technology is limited by immunological barriers and the time needed for culture amplification. We studied the feasibility of using human fetal skin cells f...

In human medicine, skin grafting is an innovative surgical technique widely used in reconstructive surgery to repair loss. This case evaluated the effectiveness of a treatment with dermal micro-grafting obtained through Rigenera® technology chronic open wound resulting from suture dehiscence limb amputation cat. Significant differences were observed between aesthetic aspects injury using tradit...

The present study attempts to compare how the patients who undergo early excision and grafting behave as compared with patients who are treated along usual conservative lines of management in centers where the resources are less than optimal. The data of 20 female patients were analyzed. Age of the patients ranged between 20 and 30 years, percentage area burn ranged between 20 and 40%, and perc...