We describe a technique of postoperative irradiation of skin cancer using plesiotherapy with Ir192 high dose rate microSelectron afterloading system (Nucletron, Veenendaal, Netherlands). The clinically defined area is drawn on the skin and the flexible 'skin applicator' is then orientated so that the drawn skin area is encompassed within the catheter defined surface. Using a thin pewter wire, t...

BACKGROUND Bullous pemphigoid is an autoimmune blistering disease, with relapses, isolated or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Joint manifestations rapidly respond to small or moderate doses of corticosteroids, whereas skin manifestations usually respond to antimalarial drugs. CASE REPORT We describe the clinical case of an 11-year-old girl w...

We reported the inhibitory effects of genistein, an inhibitor of tyrosine protein kinase (TPK), on ultraviolet B (UVB)-induced expression of c-fos and c-jun in SENCAR mouse skin. UVB irradiation substantially increased transcript levels of c-fos and c-jun mRNA in mouse skin. Topical application of genistein 60 min before UVB radiation reduced c-fos and c-jun expression in the mouse skin in dose...

Dental panoramic tomography is a technique by which an image of the entire dentition may be obtained on a single film, without superimposition of superficial structures or deeper than teeth and jaws. These machines are characterized by the fact that the tube and the cassette holder are mobile, so they rotate from one side of the patient’s head around his back to the other side. During this moti...

Methods and results A 75-year old male suffering from erysipelas received simultaneous treatment with oral clindamycin and i.v. penicillin G, which later was switched to oral penicillin. After eight days of antibiotic therapy an erythematous maculopapular exanthema developed on his trunk and extremities. Treatment was changed to cefuroxime, topical steroids initiated and the skin rash slowly va...

IMPORTANCE Solar UV irradiation causes photoaging, characterized by fragmentation and reduced production of type I collagen fibrils that provide strength to skin. Exposure to UV-B irradiation (280-320 nm) causes these changes by inducing matrix metalloproteinase 1 and suppressing type I collagen synthesis. The role of UV-A irradiation (320-400 nm) in promoting similar molecular alterations is l...

PURPOSE To determine peak skin dose (PSD), a measure of the likelihood of radiation-induced skin effects, for a variety of common interventional radiology and interventional neuroradiology procedures, and to identify procedures associated with a PSD greater than 2 Gy. MATERIALS AND METHODS An observational study was conducted at seven academic medical centers in the United States. Sites prosp...

Sir, Skin rashes have been associated with COVID-19 and studies suggest the inclusion of skin diseases in list symptoms. eruptions are also mRNA-1273 vaccine. Findings by Baden et al. [1] describe immediate injection-site reactions observed 84.2% participants after first dose, delayed onset reactions—on or day eight—occurring much more infrequently, 0.8% dose 0.2% second dose. Blumenthal [2] di...

Introduction: Contura is a balloon applicator that used to deliver intra cavity radiation for Partial Breast Irradiation (PBI) treatments. Contura with 4 peripheral lumens surrounding the central, for loading HDR sources from an after loader system can provide an asymmetric dose distribution and gives a more flexible shape of dose than earlier balloon applicators such as Mammo...

Survival sepsis campaign recommends that vasopressor therapy is required to maintain mean arterial pressure (MAP) ≥ 65 mmHg. However, the absolute maximum dose of vasopressor is difficult to determine. Herein, we report 2 cases of severe skin necrosis after high dose vasopressor infusion to maintain the recommended MAP in septic shock. In our first case, norepinephrine 1.0-2.0 μg/kg/min and vas...