Two cases of anticonvulsant megaloblastic anaemia are described, showing features of unusual interest. Though both cases were apparently deficient in folic acid, the Figlu tests were negative. One patient had an extremely low serum B(12) concentration apparently associated with defective B(12) absorption due to deficiency of intrinsic factor, and both showed impaired intestinal absorption of D-...

The COVID-19 pandemic involved the globe and resulted in major mortalities mainly affecting respiratory system. Initially thought to be disease it was later postulated confirmed involvement of gastro-intestinal tract (GIT) its contribution complications mortalities. Herein we present five cases severe infection with GI their management literature review.

Conglutins represent the major peanut allergens and are renowned for their resistance to gastro-intestinal digestion. Our aim was to characterize the digestion-resistant peptides (DRPs) of conglutins by biochemical and biophysical methods followed by a molecular dynamics simulation in order to better understand the molecular basis of food protein allergenicity. We have mapped proteolysis sites ...

Introduction: The upper gastro-intestinal bleed is one of the most common indication for endoscopy. There are various reasons same and include gastric or duodenal ulcer, erosive gastritis duodenitis, esophagitis, mallory weiss tear, malignancy etc. Many prisoner feign to be having hematemesis but their history clinical presentation does not match with it.

Successful delivery of promising new chemical entities via the oral route is rife with challenges, some of which cannot be explained or foreseen during drug development. Further complicating an already multifaceted problem is the obvious, yet often overlooked, effect of dietary substances on drug disposition and response. Some dietary substances, particularly fruit juices, have been shown to in...