Lectins are biomolecules with high affinity and narrow range of specificity for defined sugar residues so that they can be used as selective probes for the detection of glycoconjugate glycosylation. A large number of lectins with differing specificities have been identified and found in a variety of plants, invertebrates and vertebrates. Due to their high specificity and multiple functions, lec...

Feature selection is a fundamental process in many classifier design problems. However, it is NP-complete and approximate approaches often require requires extensive exploration and evaluation. This paper describes a novel approach that represents feature selection as a continuous regularization problem which has a single, global minimum, where the model s complexity is measured using a 1-norm ...

In the last few years, environmental sequence surveys have identified several putative novel lineages within the eukaryotes. This interpretation is however limited by the absence of taxon sampling for several well known and abundant eukaryotes (Cavalier-Smith 2004; Simpson and Roger 2004). It is therefore important to complement classical morphological studies with molecular sequencing, as well...

In "Functional MRI Lie Detection: Too Good to be True?" in this issue of The Journal, Joseph Simpson reviews the merits and the limitations of using fMRI to detect deception. After presenting the gaps in experimental data that stand in the way of translating the laboratory proof of concept to a field application, Simpson surveys the legal, regulatory and ethics concerns facing fMRI, should it e...