The aim of the present study was to analyse sequences of 16S-23S internal transcribed spacer regions of different Geobacillus species, identify structural elements of these regions and evaluate the possibility to use these structural elements in the taxonomy of the genus Geobacillus. GEOBAC-PCR was used in order to obtain 16S-23S rRNA internal transcribed spacer sequences. Certain structural el...

Glutaredoxins are enzymatic antioxidants which are small, ubiquitous, glutathione dependent and essentially classified under thioredoxin-fold superfamily. Glutaredoxins are classified into two types: dithiol and monothiol. Monothiol glutaredoxins which carry the signature "CGFS" as a redox active motif is known for its role in oxidative stress, inside the cell. In the present analysis, the 138 ...

Abstract. A classical result of MacMahon shows that the length function and the major index are equidistributed over the symmetric groups. Through the years this result was generalized in various ways to signed permutation groups. In this paper we present several new generalizations, in particular, we study the effect of different linear orders on the letters [−n, n] and generalize a classical ...

The regulation of cleavage plane orientation is one of the key mechanisms driving epithelial morphogenesis. Still, many aspects of the relationship between local cleavage patterns and tissue-level properties remain poorly understood. Here we develop a topological model that simulates the dynamics of a 2D proliferating epithelium from generation to generation, enabling the exploration of a wide ...

A new variant allele CYP2D6*62 (g.4044C>T; R441C) of the drug-metabolizing cytochrome P450 (P450) CYP2D6 was identified in a person with reduced sparteine oxidation phenotype, which was unexpected based on a genetic CYP2D6*1A/*41 background. The recombinantly expressed variant protein had no activity toward propafenone as a result of missing heme incorporation. Sequence alignment revealed that ...

Horizontal DNA transfer is an important factor of evolution and participates in biological diversity. Unfortunately, the location and length of horizontal transfers (HTs) are known for very few species. The usage of short oligonucleotides in a sequence (the so-called genomic signature) has been shown to be species-specific even in DNA fragments as short as 1 kb. The genomic signature is therefo...

In this paper, the design of signature waveforms for asynchronous CDMA systems equipped with a correlation receiver is first considered. Optimal signature waveforms that minimize the average multiple access interference (MAI) at the output of a correlation receiver are found, while satisfying the constraint on available transmission bandwidth. Comparison to signature waveforms previously obtain...

A redactable signature scheme is one that allows the original signature to be used, usually along with some additional data, to verify certain carefully specified changes to the original document that was signed, namely the removal or redaction of subdocuments. For redactable signatures, the term transparency has been used to describe a scheme that hides the number and locations of redacted sub...

Fatty acid amide hydrolase (FAAH) is a mammalian integral membrane enzyme responsible for the hydrolysis of a number of neuromodulatory fatty acid amides, including the endogenous cannabinoid anandamide and the sleep-inducing lipid oleamide. FAAH belongs to a large class of hydrolytic enzymes termed the "amidase signature family," whose members are defined by a conserved stretch of approximatel...

When Einstein was thinking about the theory of general relativity based on the elimination of especial relativity constraints (especially the geometric relationship of space and time), he understood the first limitation of especial relativity is ignoring changes over time. Because in especial relativity, only the curvature of the space was considered. Therefore, tensor calculations should be to...