نتایج جستجو برای: signal molecule

تعداد نتایج: 542076  

Journal: :Journal of neurochemistry 2008
David R Linden Lei Sha Amelia Mazzone Gary J Stoltz Cheryl E Bernard Julie K Furne Michael D Levitt Gianrico Farrugia Joseph H Szurszewski

The gaseous molecule hydrogen sulfide (H(2)S) has been proposed as an endogenous signal molecule and neuromodulator in mammals. Using a newly developed method, we report here for the first time the ability of intact and living brain and colonic tissue in the mouse to generate and release H(2)S. This production occurs through the activity of two enzymes, cystathionine-gamma-lyase and cystathioni...

Journal: :Journal of Low Power Electronics and Applications 2022

Molecular Field-Coupled Nanocomputing (FCN) is a computational paradigm promising high-frequency information elaboration at ambient temperature. This work proposes model to evaluate the signal energy involved in propagating and elaborating information. It splits evaluation into several contributions calculated with closed-form expressions without computationally expensive calculation. The essen...

2014
Yanhui Zhao Danqi Chen Hongjun Yue Michelle M. Spiering Chenglong Zhao Stephen J. Benkovic Tony Jun Huang

The ability of zero-mode waveguides (ZMWs) to guide light energy into subwavelength-diameter cylindrical nanoapertures has been exploited for single-molecule fluorescence studies of biomolecules at micromolar concentrations, the typical dissociation constants for biomolecular interactions. Although epi-fluorescence microscopy is now adopted for ZMW-based imaging as an alternative to the commerc...

Journal: :The Journal of chemical physics 2012
L K Dash H Ness M J Verstraete R W Godby

We analyze how functionality could be obtained within single-molecule devices by using a combination of non-equilibrium Green's functions and ab initio calculations to study the inelastic transport properties of single-molecule junctions. First, we apply a full non-equilibrium Green's function technique to a model system with electron-vibration coupling. We show that the features in the inelast...

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