To interrelate in vivo wall shear stress, endothelial microfilament bundle formation, and atherosclerosis localization, we used a mild abdominal aortic stenosis in 11 beagles to produce a range of wall shear stresses above and below the constriction. Six of the beagles were fed standard animal chow supplemented with 5% cholesterol and 10% coconut oil. Wall shear stresses, endothelial microfilam...

Measurements of the yield behaviour of a cohesive bulk solid in the Jenike shear tester are normally done in two steps. First, pre-shearing to a steady state yielding, and secondly, shearing under a lower normal stress to establish the shear stress at incipient failure. Due to the limited strain of the sample in this apparatus, the material must be consolidated in an earlier stage. This is done...

The mechanical function of soft collagenous tissues is largely determined by their hierarchical organization of collagen molecules. While collagen fibrils are believed to be discontinuous and transfer load through shearing of the interfibrillar matrix, interfibrillar shear stresses have never been quantified. Scaling traditional shear testing procedures down to the fibrillar length scale is imp...

13 In the shear deformation of powder beds beyond the quasi-static regime the shear stress is dependent 14 on the strain rate. Extensive work has been reported on the rapid chute flow of large granules but the 15 intermediate regime has not been widely addressed particularly in the case of cohesive powders. 16 However in industrial powder processes the powder flow is often in the intermediate r...

A numerical investigation of the effects of nanosecond barrier discharge on the stability of a two-dimensional free shear layer is performed. The computations are carried out using a compressible Navier-Stokes algorithm coupled with a thermodynamic model of the discharge. The results show that significant increases in the shear layer’s momentum thickness and Reynolds stresses occur due to actua...

We report measurements of the static shear modulus of electrorheological (ER) fluids consisting of water-wetted silica microspheres in silicone oil. A shear-annealing method, using creep-recovery (CR) cycles under an external electric field, is used to enhance ER properties of the fluid. The shear-annealing method enables the silica spheres in the ER fluid to form better aligned and denser colu...

In this paper, the effects of horizontal stress and dimensions of barrier pillars on the stability of drifts hr been investigated. An elastoplastic hybrid finite/boundary element program has been used. A plastic analysis of stresses in barrier pillars above the drifts in one of the underground coal mines with inclined seams is examined. Computed stresses and safety factor controur lines around ...

The distribution of the wall shear stress on the bed and sidewalls of an open channel receiving lateral inflow was obtained from experimental measurements of the distribution of the velocity in the viscous sublayer using a laser doppler velocimeter. The experiments were conducted in a 0.4 m wide by 7.5 m long flume. Lateral inflow was provided into the channel from above via sets of nozzles pos...

Exposure of citrated human platelet-rich plasma (C-PRP) to mechanical shear stress has been shown to induce platelet aggregation (PAG), release from platelets of dense granule contents, and platelet lysis. The mechanisms involved in these shear-induced platelet alterations have not been defined. To examine the possible role of prostaglandin (PG) synthesis in shear-induced platelet reactions, C-...