We conduct a two-dimensional numerical experiment on the lower crust under an intraplate strike-slip fault based on laboratory-derived power-law rheologies considering the effects of grain size and water. To understand the effects of far-field loading and material properties on the deformation of the lower crust on a geological time scale, we assume steady fault sliding on the fault in the uppe...

The concept of enhancing structural integrity of mitochondria has emerged as a novel therapeutic option for cardiovascular disease. Flow-induced increase in laminar shear stress is a potent physiological stimulant associated with exercise, which exerts atheroprotective effects in the vasculature. However, the effect of laminar shear stress on mitochondrial remodeling within the vascular endothe...

The effect of transverse shear on delamination in layered, isotropic, linear-elastic materials has been determined. In contrast to the effects of an axial load or a bending moment on the energy-release rate for delamination, the effects of shear depend on the details of the deformation in the crack-tip region. It therefore does not appear to be possible to deduce rigorous expressions for the sh...

The rheology of bubble-bearing suspensions is investigated through a series of three-dimensional boundary integral calculations in which the effects of bubble deformation, volume fraction, and shear rate are considered. The behaviour of bubbles in viscous flows is characterized by the capillary number, Ca, the ratio of viscous shear stresses that promote deformation to surface tension stresses ...

We model the acceleration of energetic particles due to shear and centrifugal effects in rotating astrophysical jets. The appropriate equation describing the diffusive transport of energetic particles in a collisionless, rotating background flow is derived and analytical steady state solutions are discussed. In particular, by considering velocity profiles from rigid, over flat to Keplerian rota...

The generation of dc magnetic fields in unmagnetized electron-ion shear flows is shown to be associated to either initial thermal effects or the onset of electron-scale shear instabilities, in particular the cold Kelvin-Helmholtz instability. This mechanism, intrinsic to shear gradients on the electron scale, is described through a kinetic model that predicts the growth and the saturation of th...

BACKGROUND Endothelial cells (ECs) are continuously exposed to hemodynamic forces imparted by blood flow. While it is known that endothelial behavior can be influenced by cytokine activation or fluid shear, the combined effects of these two independent agonists have yet to be fully elucidated. METHODOLOGY We investigated EC response to long-term inflammatory cues under physiologically relevan...

Vasoactive drugs are known to affect impedance (pressure/flow) and vessel wall motion in arteries. The nonlinear theory of oscillatory flow in straight elastic vessels indicates that wall shear rate is affected by changes in impedance phase angle and wall motion. To test whether wall shear rate depends on impedance phase angle and wall motion in vivo, wall shear rate was measured in the abdomin...

Dinoflagellates have proven extremely difficult to culture because they are inhibited by low-level shear forces. Specific growth rate of the toxic dinoflagellate Protoceratium reticulatum was greatly decreased compared with static control culture by intermittent exposure to a turbulent hydrodynamic environment with a bulk average shear rate that was as low as 0.3 s(-1). Hydrodynamic forces appe...

Several bulk model–based entrainment parameterizations for the atmospheric convective boundary layer (CBL) with wind shear are reviewed and tested against large-eddy simulation (LES) data to evaluate their ability to model one of the basic integral parameters of convective entrainment—the entrainment flux ratio. Test results indicate that many of these parameterizations fail to correctly reprod...