Fetuses of mothers with gestational diabetes mellitus are at increased risk to develop perinatal complications mainly due to macrosomia. However, in view of the marked heterogeneity of this disease, it seems difficult to set guidelines for diagnosis and treatment. This complicates the choice of assigning patients either to diet or to insulin therapy. Also of concern is how much benefit could be...

OBJECTIVE To assess the effect of a publicly funded domestic heating programme on self-reported health. DESIGN, SETTING AND PARTICIPANTS A prospective controlled study of 1281 households in Scotland receiving new central heating under a publicly funded initiative, and 1084 comparison households not receiving new heating. The main outcome measures were self-reported diagnosis of asthma, bronch...

We report the characterization of a suspended microchannel resonator (SMR) for viscosity measurements in a low viscosity regime (<10 mPa s) using two measurement schemes. First, the quality factor (Q-factor) of the SMR was characterized with glycerol-water mixtures. The measured Q-factor at 20 °C exhibits a bilinear behavior with the sensitivity of 1281 (mPa s)(-1) for a lower (1-4 mPa s) and 3...

CHOI, PRECILLA Y. L. (2000) Femininity and the Physically Active Woman, Routledge, London. COOK, GRETCHEN (2003) 'POWs likely to endure sexual assault', Women's Enews. [Online] Available at: http://www.womenenews.org/article.cfm/dyn/aid/1281/context/ archive (6 July 2004). ISKANDER, MONA (2003) ISKANDER, MONA (2004) 'Female troops in Iraq redefine combat rules', Women's Enews, [Online] Availabl...

Purpose: Src is overexpressed or hyperactivated in a variety of human cancers, including thyroid carcinoma. Src is a central mediator in multiple signaling pathways that are important in oncogenesis and cancer progression. In this study, we evaluated the effects of an Src inhibitor, SKI-606 (bosutinib), in a spontaneous metastatic thyroid cancer model with constitutively activated Src (ThrbPV/P...

Objective: Evaluate the effect of transcranial direct current stimulation (tDCS) combined with reading therapy on performance tasks in a serie cases children and adolescents developmental dyslexia (DD). Method: (IRB/UNIFESP number:1281/2017). Four dyslexic students (two two adolescents) were evaluated regards to rate accuracy fluency three occasions: pre-intervention as well one six months afte...

Background: Glycogen synthase 2 (GYS2) catalyzes a key step in glycogenesis the liver. Loss-of-function mutations GYS2 gene are associated with type 0a glycogenosis characteristic fasting hypoglycemia and postprandial hyperglycemia. The association of single nucleotide polymorphism rs10841855 (G&gt;T) risk diabetes mellitus (T2D) was first established European population, but data on effect thi...

Weight loss is a common problem after gastric cancer surgery. It also related to decrease of patient’s quality life and the compliance postoperative chemotherapy. Some clinicians insist weight itself can affect survival. We reviewed change gastrectomy in 1,421 patients. The BMI trajectory model showed significant at 6 months gastrectomy. Severe loss（mean 21.5％；n=109）was significantly associated...

Expression of the adhesion molecules CD44, L-selectin (CD62L), and integrin a 4 b 7 by antibody-secreting cells (ASC) was examined in human volunteers after oral, rectal, intranasal, or systemic immunization with cholera toxin B subunit. Almost all blood ASC, irrespective of immunization route, isotype (IgG and IgA), and immunogen, expressed CD44. On the other hand, marked differences were obse...

BACKGROUND This meta-analysis was conducted to evaluate whether HTR1A gene polymorphisms impact the efficacy of antipsychotic drugs in patients with schizophrenia. METHODS Candidate gene studies that were published in English up to August 6, 2015 were identified by a literature search of PubMed, Web of Science, and Google scholar. Data were pooled from individual clinical trials considering o...