OBJECTIVE It is unknown whether a low-fat diet, which may elevate triglycerides and lower high-density lipoprotein (HDL) cholesterol, harms the endothelium. Our aim was to determine whether a low-fat, high-carbohydrate (CARB) diet impaired endothelial vasodilation compared with high saturated fat (SFA), monounsaturated fat (MUFA), or polyunsaturated fat (PUFA) diets. METHODS AND RESULTS Forty...

Slow feature analysis (SFA) is a new unsupervised algorithm to learn nonlinear functions that extract slowly varying signals out of the input data. In this paper we describe its application to pattern recognition. In this context in order to be slowly varying the functions learned by SFA need to respond similarly to the patterns belonging to the same class. We prove that, given input patterns b...

Few well-controlled diet studies have investigated the effects of reducing dietary saturated fatty acid (SFA) intake in premenopausal and postmenopausal women or in blacks. We conducted a multicenter, randomized, crossover-design trial of the effects of reducing dietary SFA on plasma lipids and lipoproteins in 103 healthy adults 22 to 67 years old. There were 46 men and 57 women, of whom 26 wer...

Few well-controlled diet studies have investigated the effects of reducing dietary saturated fatty acid (SFA) intake in premenopausal and postmenopausal women or in blacks. We conducted a multicenter, randomized, crossover-design trial of the effects of reducing dietary SFA on plasma lipids and lipoproteins in 103 healthy adults 22 to 67 years old. There were 46 men and 57 women, of whom 26 wer...

The occurrence of fim, pap, sfa, and afa genes was evaluated in 200 Escherichia coli strains isolated from chickens diagnosed with omphalitis, salpingitis, swollen head syndrome, or chronic respiratory disease. Analysis of the strains by colony hybridization tests demonstrated that 96% of the isolates were fim, 16% were pap, and 6% were sfa. None of the isolates was afa. The fim gene occurred i...

A cell-type-specific membrane glycoprotein (SFA) of chicken (1) and human (2) fibroblasts has been recently described from our laboratory . Malignantly transformed fibroblasts lack SFA on their surface (3) . The same antigen is present in serum and its molecular properties are similar to those of the cellular antigen (4). The surface labeled protein present on normal but not on transformed hams...

Methods Thirteen female New Zealand White rabbits were randomized to receive either intramuscular sham injection (n=4), empty capsules (n=4) or microencapsulated MSCs (n=5) in the medial thigh 24h after endovascular occlusion of the left superficial femoral artery (SFA). Three-dimensional (3D) TOF MRA acquired in the axial plane (3T Trio Siemens, 30ms TR; 3.69ms TE; 0.6×0.4×0.6mm voxel size), 3...

The long-term effect of two surgical techniques for repair of coarctation of the aorta in infancy, namely, resection and end-to-end anastomosis (RETE) and subclavian flap angioplasty (SFA) on the blood supply of the upper left limb, was quantified by Doppler spectrum analysis of blood flow velocities in the left brachial artery at rest and during postocclusive reactive hyperemia. Twenty-three p...

Genome-wide association studies (GWAS) have uncovered numerous variants associated with body mass index (BMI), waist circumference, and waist-to-hip ratio. Our study aims to investigate how these variants are linked to fat distribution. We genotyped 56 validated variants of BMI, waist circumference, and waist-to-hip ratio in 2958 subjects from Chinese community-based populations and performed l...

The measurement of body composition is of value in the nutritional assessment of patients with chronic obstructive pulmonary disease (COPD). The purpose of the present study was to compare two bedside methods for the measurement of body composition using dual energy X-ray absorptiometry (DEXA) as a reference method. Fat-free mass (FFM) was measured using DEXA, bioelectric impedance analysis (BI...