background: formaldehyde (h2c = o), is a member of aldehyde family with a simplest organic molecule, used in various industries. the aim of this experimental study was to investigate the effects of simultaneous formaldehyde and noise exposure on hormonal pituitary-gonadal axis in adult male mice. methods: 46 adult male mice were randomly assigned to one control group and three experimental grou...

Although endometriosis is suspected to be a cause of premature ovarian insufficiency (POI), the mechanism(s) underlying this process have not been elucidated. Recently, androgens were shown to promote oocyte maturation and to play a role in folliculogenesis. In addition, several reports have documented low testosterone levels in the follicular fluid obtained from endometriosis patients. We ther...

In order to throw further light on the role of androgens in the aetiology of the polycystic ovary syndrome (PCO) we have examined the effect of artificially increasing serum testosterone levels on menstrual function in a group of ovulating women. Six women were studied who had either severe premenstrual syndrome or loss of libido for which they were treated with 100 mg testosterone by s.c. impl...

Low levels of serum testosterone are characteristically associated with diabetes, coronary atherosclerosis, obstructive sleep apnea, rheumatoid arthritis, and chronic obstructive pulmonary disease. Testosterone replacement therapy is effective against many of these disorders, indicating the importance of maintaining a healthy testosterone level. In this study, we investigated the effects of fis...

OBJECTIVE Primary - to determine the age of pubertal onset in Indian boys. Secondary - (a) to assess the impact of obesity on pubertal timing, (b) to assess the relationship between gonadotropins and puberty. DESIGN Cross-sectional. SETTING General community-seven schools across New Delhi. PARTICIPANTS Random sample of 1306 school boys, aged 6-17 years. MATERIALS AND METHODS Anthropomet...

In the work the results of the research aimed to determine the peculiarities of changes in the content of testosterone in the blood of people of different level of fitness under the influence of acute power load in the process of long trainings athleticism. The surveys were performed with the participation of 20 athletes age of 19-20 years, regularly engaged in athleticism over 3 years, and 20 ...

Background: Many studies have been carried out on the relationship between testosterone levels and depression in the elderly. Due to the different results of these studies and the importance of depression in old age, this study seems to be necessary. Methods: This cross- sectional study is a part of the Amirkola Health and Aging Project (AHAP) that involves people aged 60 and above living in A...

BACKGROUND Low serum testosterone is a common condition in aging associated with decreased muscle mass and insulin resistance. This study evaluated whether low testosterone levels are a risk factor for mortality in male veterans. METHODS We used a clinical database to identify men older than 40 years with repeated testosterone levels obtained from October 1, 1994, to December 31, 1999, and wi...

Kallmann's syndrome is a neuronal migration disorder characterised by anosmia/hyposmia and hypogonadotropic hypogonadism. We present a case of a 21-year-old man who was unable to sense smell since birth and who displayed non-development of secondary sexual characteristics for the past 10 years. Blood investigations showed low basal levels of serum follicle stimulating hormone (FSH), serum lutei...