Researchers add serum to a classical medium at concentrations of 5 to 10% (v/v) to grow cellsin-vitro culture media. Unfortunately, serum is a poorly defined culture medium componentas its composition can vary considerably while serum-free cell culture media are an excellentalternative to standard serum-containing media and offer several major advantages. Advantagesof us...

Background: Urtica dioica is known as an anti-hyperglycemic plant. Urtica dioica distillate (UD) is a traditional Iranian drink, locally known as “aragh gazaneh”. In spite of its widespread consumption in Iran, according to traditional Iranian medicine, there is no scientific report on the usefulness of UD for diabetic patients. This survey was designed to evaluate its protective effects for th...

Background Serum uric acid (UA) has been reported as a risk factor for type 2 diabetes mellitus (T2DM). However, whether serum UA is associated with insulin resistance and insulin secretion, and the effect of gender on it in the case of the existed association, both remain undefined. Methods A cross-sectional study was designed and performed, which enrolled a total of 403 newly diagnosed T2DM...

diabetes is a metabolic disorder specified by hyperglycemia following a defect in insulin secretion, insulin resistance or both. the aim of this study was to examine the effect of high-intensity interval training (hiit) on serum adiponectin levels and insulin resistance of women with type 2 diabetes. for this purpose, 35 overweight women with type 2 diabetes (age range 45-60 years, bmi 25-30 kg...

Background: Diabetes mellitus, a group of metabolic disorder with multiple etiologies is characterized by chronic hyperglycaemia, induced deficiency insulin production and action. Prediabetes type hyperglycemia in which glycemic indices are higher than normal but lower the diabetes threshold. Objective: This study aims to assess impact bone markers (serum calcium, phosphorus alkaline phosphatas...

there are many reports for involvement of atp-sensitive potassium channels in pancreatic, cardiac and vascular smooth muscle cells. this study examined the effect of single doses of k+ channel openers diazoxide, minoxidil and k+ channel blockers chlorpropamide, glibenclamide on serum concentration of aldosterone in male rats. blood samples were obtained 60 minutes after drug treatment and serum...

    Background: Nowadays, Alzheimer’s disease (AD) is considered as Type 3 diabetes in which insulin resistance is the common cause of both diseases. Disruption of insulin signaling cascade and insulin resistance can induce AD; and central insulin resistance causes systemic alterations in serum insulin, FBS levels, and lipid profile. Studies have shown that probiotics (Lact...